CAJ | 학술논문

Coats病是一种儿童多见的眼底病,典型临床表现是视网膜毛细血管扩张伴视网膜层间及视网膜下的渗出.本病发病机制不明确,受累眼视力预后不佳,严重的患者可因并发症导致眼球摘除.目前认为其发病机制与血管因素、基因及细胞因子相关.其治疗方法包括激光、冷冻及药物治疗,多采取联合治疗.玻璃体手术治疗作为复杂病例可选择的方法,但应慎重.
Coats병시일충인동다견적안저병,전형림상표현시시망막모세혈관확장반시망막층간급시망막하적삼출.본병발병궤제불명학,수루안시력예후불가,엄중적환자가인병발증도치안구적제.목전인위기발병궤제여혈관인소、기인급세포인자상관.기치료방법포괄격광、냉동급약물치료,다채취연합치료.파리체수술치료작위복잡병례가선택적방법,단응신중.
Coats disease is mostly unilateral and affects mainly males during childhood.It characterizes by retinal telangiectasis,intraretinal and subretinal exudation.The pathogenesis of Coats dieases is still unclear.The affected eye usually has poor prognosis,and enucleation may be considered in some of severe patients.In current,the pathogenesis is considered related to the vascular factors,genes,and cytokines.The treatments of Coats disease include laser,cryotherapy,and medications,and the combined therapy is the commom choice.The vitrectomy can be choose for the refractory cases,while the surgery should be carefully choosed.