当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2015年
10期
90-90,91
,共2页
恶性肿瘤%弥散性血管内凝血%D-二聚体%感染
噁性腫瘤%瀰散性血管內凝血%D-二聚體%感染
악성종류%미산성혈관내응혈%D-이취체%감염
Malignancy tumor%Disseminated intravascular coagulation%D-dimer%Infection
目的:分析恶性肿瘤合并弥散性血管内凝血(DIC)合并感染患者血浆D-二聚体水平。方法选取肿瘤性DIC患者39例(1组)、肿瘤性DIC合并感染患者42例(2组),健康人40名(对照组),采用全自动血凝仪进行检测,用免疫比浊法测受试者血浆D-二聚体的值。结果对照组D-二聚体测值(0.74±0.35)mg/L,中位数0.8 mg/L,四分位数间距0.5 mg/L,病死率为0%,无人死亡;1组D-二聚体测值(7.81±9.33)mg/L,中位数5.4 mg/L,四分位数间距7.580 mg/L,病死率为64.1%,死亡24名;与对照组D-二聚体值以及病死率比较,差异有统计学意义(P<0.05)。2组D-二聚体测值(14.6±13.6)mg/L,中位数10.8 mg/L,四分位数间距11.975 mg/L,病死率88.1%,死亡37名;与对照组D-二聚体值及病死率比较,差异有统计学意义(P<0.05);与1组D-二聚体值及病死率比较,差异有统计学意义(P<0.05)。结论肿瘤性DIC合并感染可使D-二聚体明显升高。
目的:分析噁性腫瘤閤併瀰散性血管內凝血(DIC)閤併感染患者血漿D-二聚體水平。方法選取腫瘤性DIC患者39例(1組)、腫瘤性DIC閤併感染患者42例(2組),健康人40名(對照組),採用全自動血凝儀進行檢測,用免疫比濁法測受試者血漿D-二聚體的值。結果對照組D-二聚體測值(0.74±0.35)mg/L,中位數0.8 mg/L,四分位數間距0.5 mg/L,病死率為0%,無人死亡;1組D-二聚體測值(7.81±9.33)mg/L,中位數5.4 mg/L,四分位數間距7.580 mg/L,病死率為64.1%,死亡24名;與對照組D-二聚體值以及病死率比較,差異有統計學意義(P<0.05)。2組D-二聚體測值(14.6±13.6)mg/L,中位數10.8 mg/L,四分位數間距11.975 mg/L,病死率88.1%,死亡37名;與對照組D-二聚體值及病死率比較,差異有統計學意義(P<0.05);與1組D-二聚體值及病死率比較,差異有統計學意義(P<0.05)。結論腫瘤性DIC閤併感染可使D-二聚體明顯升高。
목적:분석악성종류합병미산성혈관내응혈(DIC)합병감염환자혈장D-이취체수평。방법선취종류성DIC환자39례(1조)、종류성DIC합병감염환자42례(2조),건강인40명(대조조),채용전자동혈응의진행검측,용면역비탁법측수시자혈장D-이취체적치。결과대조조D-이취체측치(0.74±0.35)mg/L,중위수0.8 mg/L,사분위수간거0.5 mg/L,병사솔위0%,무인사망;1조D-이취체측치(7.81±9.33)mg/L,중위수5.4 mg/L,사분위수간거7.580 mg/L,병사솔위64.1%,사망24명;여대조조D-이취체치이급병사솔비교,차이유통계학의의(P<0.05)。2조D-이취체측치(14.6±13.6)mg/L,중위수10.8 mg/L,사분위수간거11.975 mg/L,병사솔88.1%,사망37명;여대조조D-이취체치급병사솔비교,차이유통계학의의(P<0.05);여1조D-이취체치급병사솔비교,차이유통계학의의(P<0.05)。결론종류성DIC합병감염가사D-이취체명현승고。
[Abstrct]Objective To explore the variaration of D-dimer of the plasma which patients with malignancy tumor of patients with disseminated intravascular coagulation(DIC) and infection.Methods 40 cases heahth people(control group) were chosen, 39 cases of malignancy tumor with DIC(the ifrst group) , 42 cases of malignancy tumor with DIC and infection(the second group). All patients came from Hunan Wang Wang Hospital. Test D-dimer of plasma by immune turbidimetry.Results The numerical mean of the control group’s D-dimer value was (0.74±0.35)mg/L,the motility rate is 0%. The numerical mean of the ifrst group’s D-dimer value was (7.81±9.33)mg/L, the motility rate was 64.1%; compared with the control’s,P<0.05; the numerical mean of the second group’s D-dimer value was (14.60±13.64)mg/L, the motility rate was 88.1%, compared with the control group’s,P<0.05; compared with the ifrst group’s,P<0.05.Conclusion D-dimer is obviously increased occurs in patients with malignancy tumor of patients with DIC and infection.