CAJ | 학술논문

目的：观察无创呼吸机治疗支气管哮喘合并肺炎的临床效果。方法选取2013年4月至2013年10月本院呼吸科住院的50例支气管哮喘合并肺炎患者为研究对象，采用随机数表法分为治疗组与对照组，每组各25例。对照组患者给予抗感染、二羟丙茶碱、甲泼尼龙琥珀酸钠、支气管扩张剂、排痰药物等对症治疗，治疗组患者在对照组基础上加用无创呼吸机辅助呼吸。观察并比较两组患者治疗前后日间、夜间症状评分，呼吸困难、咳嗽、肺部干/湿性啰音等体征消失时间，住院天数，治疗前后PaO2、PaCO2、SaO2水平变化及疗效。结果治疗组患者治疗总有效率为96.0%（24/25），明显高于对照组[60.0%（15/25）]，差异具有显著性（P＜0.05)。治疗后两组患者日间、夜间症状评分均明显高于治疗前，且治疗组评分明显高于对照组（P＜0.05）。治疗组患者呼吸困难、咳嗽、肺部干/湿性啰音等体征消失时间及住院天数均明显短于对照组，差异均具有显著性（P＜0.05）。两组患者治疗后PaO2、SaO2水平均明显高于治疗前，PaCO2水平低于治疗前，差异均具有显著性（P＜0.05）。治疗组患者治疗后PaO2、SaO2水平均明显高于对照组，PaCO2水平低于对照组，差异均具有显著性（P＜0.05）。结论无创呼吸机对支气管哮喘合并肺炎患者的治疗效果显著，可明显改善患者临床症状，提高肺功能，值得临床推广应用。
목적：관찰무창호흡궤치료지기관효천합병폐염적림상효과。방법선취2013년4월지2013년10월본원호흡과주원적50례지기관효천합병폐염환자위연구대상，채용수궤수표법분위치료조여대조조，매조각25례。대조조환자급여항감염、이간병다감、갑발니룡호박산납、지기관확장제、배담약물등대증치료，치료조환자재대조조기출상가용무창호흡궤보조호흡。관찰병비교량조환자치료전후일간、야간증상평분，호흡곤난、해수、폐부간/습성라음등체정소실시간，주원천수，치료전후PaO2、PaCO2、SaO2수평변화급료효。결과치료조환자치료총유효솔위96.0%（24/25），명현고우대조조[60.0%（15/25）]，차이구유현저성（P＜0.05)。치료후량조환자일간、야간증상평분균명현고우치료전，차치료조평분명현고우대조조（P＜0.05）。치료조환자호흡곤난、해수、폐부간/습성라음등체정소실시간급주원천수균명현단우대조조，차이균구유현저성（P＜0.05）。량조환자치료후PaO2、SaO2수평균명현고우치료전，PaCO2수평저우치료전，차이균구유현저성（P＜0.05）。치료조환자치료후PaO2、SaO2수평균명현고우대조조，PaCO2수평저우대조조，차이균구유현저성（P＜0.05）。결론무창호흡궤대지기관효천합병폐염환자적치료효과현저，가명현개선환자림상증상，제고폐공능，치득림상추엄응용。
Objective To observe the clinical efifcacy of noninvasive respirator in treating bronchial asthma combined with pneumonia. Method 50 patients with bronchial asthma combined pneumonia admitted by the hospital chose from April 2013 to October 2013 in our hospital were divided into treatment group and control group by random indication method, 25 cases in each group. Patients in control group were treated with infection resistance, diprophylline and methyl prednisolone sodium succinate, bronchodilator, sputum excretion medicine and other symptomatic treatments. Patients in treatment group were combined with assisted respiration of noninvasive respirator on the basis of control group. The symptom scores at night and in the daytime, dyspnea, cough, disappearance time for dry and moisture rales, days of hospitalization, changes in levels of PaO2, PaCO2 and SaO2 levels before and after the treatment and efifcacy were observed and compared. Result The total effective rate in treatment group was 96.0%(24/25), signiifcantly higher than control group [60.0%(15/25)], the difference was signiifcant (P<0.05). After treatment daytime, nighttime symptom scores of the two groups were significantly higher than those before treatment, and scores of treatment group was signiifcantly higher than that of control group (P<0.05). Dififculty breathing, cough, lung wet rales and other signs disappeared time and days of hospitalization with the patients in treatment group after treatment were signiifcantly shorter than control group, difference was signiifcant (P<0.05). The two groups of patients after treatment, PaO2 and SaO2 levels were signiifcantly higher than those before treatment, the level of PaCO2 was lower than that before treatment, the difference was signiifcant (P<0.05). After treatment the levels of PaCO2 and SaO2 in treatment group patients were signiifcantly higher than control group, PaCO2 levels were lower than control group, the difference was signiifcant (P < 0.05). Conclusion Noninvasive respirator delivers signiifcant efifcacy on bronchial asthma combined pneumonia, and signiifcantly improve the clinical symptoms of patients and lung function, worthy of popularization and applications in clinical practices.