CAJ | 학술논문

微滤技术已广泛应用于食品工业、生物制药和污水处理等行业，但在微滤过程中，蛋白质对膜的污染是导致膜分离效率降低和通量下降的关键所在。本研究通过改变溶液浓度、跨膜压差来研究蛋白质溶液在死端微滤过程中对膜的污染，并对膜污染机理进行了初步探索。实验结果表明，本实验条件下，过滤过程中蛋白质聚集体在膜表面的堆积形成滤饼是造成膜污染的关键因素，通过非线性回归分析，得出最优模型为滤饼过滤模型。
미려기술이엄범응용우식품공업、생물제약화오수처리등행업，단재미려과정중，단백질대막적오염시도치막분리효솔강저화통량하강적관건소재。본연구통과개변용액농도、과막압차래연구단백질용액재사단미려과정중대막적오염，병대막오염궤리진행료초보탐색。실험결과표명，본실험조건하，과려과정중단백질취집체재막표면적퇴적형성려병시조성막오염적관건인소，통과비선성회귀분석，득출최우모형위려병과려모형。
Microfiltration technology is widely applied in the food industry、bio pharmaceutical,sewage treatment and so on. However, the key to decline of membrane separation efficiency and membrane flux is membrane fouling by protein. The study on the fouling of PVDF membrane under dead-end microfiltration of BSA by altering solution concentrations and TMPs was conducted , and the membrane fouling mechanism was explored. The experiment results indicated that the accumulation of protein aggregates on the membrane surface was the critical factor to membrane fouling under our experimental conditions. Meantime , the optimum model was cake filtration model by nonlinear regression analysis.