CAJ | 학술논문

比较桃叶鸦葱、蕨菜、苦菜3种野菜水提液对高血脂小鼠血脂代谢的影响。制备高血脂小鼠模型，采用试剂盒方法测定血浆中血清总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）和丙二醛（MDA）的水平以及超氧化物歧化酶（SOD）活力。桃叶鸦葱、蕨菜、苦菜3种野菜水提液均能降低高血脂小鼠TC、LDL-C和MDA的水平，提高HDL-C水平和SOD酶活力。与高血脂模型组相比，处理各组有显著差异，并呈现剂量依赖性。桃叶鸦葱、蕨菜、苦菜3种野菜水提液都具有良好的降血脂作用，其机制可能与阻断脂质过氧化有相关，并且桃叶鸦葱水提液降低TG水平，提高HDL-C水平和SOD酶活力的效果优于蕨菜、苦菜水提液，苦菜水提液降低TC的作用优于桃叶鸦葱、蕨菜水提液。
비교도협아총、궐채、고채3충야채수제액대고혈지소서혈지대사적영향。제비고혈지소서모형，채용시제합방법측정혈장중혈청총담고순（TC）、감유삼지（TG）、고밀도지단백담고순（HDL-C）、저밀도지단백담고순（LDL-C）화병이철（MDA）적수평이급초양화물기화매（SOD）활력。도협아총、궐채、고채3충야채수제액균능강저고혈지소서TC、LDL-C화MDA적수평，제고HDL-C수평화SOD매활력。여고혈지모형조상비，처리각조유현저차이，병정현제량의뢰성。도협아총、궐채、고채3충야채수제액도구유량호적강혈지작용，기궤제가능여조단지질과양화유상관，병차도협아총수제액강저TG수평，제고HDL-C수평화SOD매활력적효과우우궐채、고채수제액，고채수제액강저TC적작용우우도협아총、궐채수제액。
To compare the effects of water extract from Scorzonera sinensis Lipsch , Pteridium aquilinum and Sonchus oleraceus L. on plasma-lipids metabolism in mice fed high fats diet.Experimental hyperlipidemia mice were formed after feeding fatty diet. Plasma total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C) and superoxide dismutase (SOD) activity were assayed.Water extract from Scorzonera sinensis Lipsch, Pteridium aquilinum and Sonchus oleraceus L. could decrease the level of TC,LDL-C and MDA,while increasing HDL-C and SOD activity in mice fed high fats diet.Compared with the hyperlipidemia group,there were significant differences among each treatment group with dose-dependent relationship. Water extract from Scorzonera sinensis Lipsch , Pteridium aquilinum and Sonchus oleraceus L. whose mechanism may relate to block lipid peroxidation all have a better lipid-lowering effect. The effect of water extract from Scorzonera sinensis Lipsch is better than that of water extract from Pteridium aquilinum and Sonchus oleraceus L. on reducing TG,and increasing HDL-C and SOD activity.The effect of water extract from Sonchus oleraceus L. was better than that of water extract from Scorzonera sinensis Lipsch and Pteridium aquilinum on reducing TC.