CAJ | 학술논문

目的：探讨2012年临床多药耐药菌的分布特点，为预防和控制多药耐药菌感染提供参考依据。方法采用Walk Away40 SI细菌分析仪对2012年1－12月临床送检的标本进行细菌鉴定和药敏试验，结果采用WHO‐N E T软件进行统计分析。结果2012年从临床送检的10826份标本中共检出病原菌3148株，其中多药耐药菌491株占15．60％，革兰阴性菌363株占73．93％，革兰阳性菌128株占26．07％，前5位病原菌依次为鲍氏不动杆菌、肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌，分别占18．33％、17．11％、16．50％、10．59％、8．56％；多药耐药菌在临床科室分布前3位的科室依次为神经外科、骨科和 IC U ，分别占26．68％、18．74％和10．39％。结论细菌的多药耐药性在临床分离菌株中非常普遍，对临床抗感染治疗构成了严重的威胁，加强医院感染监测和采取有效的预防和控制措施具有十分重要的意义。
목적：탐토2012년림상다약내약균적분포특점，위예방화공제다약내약균감염제공삼고의거。방법채용Walk Away40 SI세균분석의대2012년1－12월림상송검적표본진행세균감정화약민시험，결과채용WHO‐N E T연건진행통계분석。결과2012년종림상송검적10826빈표본중공검출병원균3148주，기중다약내약균491주점15．60％，혁란음성균363주점73．93％，혁란양성균128주점26．07％，전5위병원균의차위포씨불동간균、폐염극뢰백균、대장애희균、동록가단포균、금황색포도구균，분별점18．33％、17．11％、16．50％、10．59％、8．56％；다약내약균재림상과실분포전3위적과실의차위신경외과、골과화 IC U ，분별점26．68％、18．74％화10．39％。결론세균적다약내약성재림상분리균주중비상보편，대림상항감염치료구성료엄중적위협，가강의원감염감측화채취유효적예방화공제조시구유십분중요적의의。
OBJECTIVE To explore the clinical distribution of multidrug‐resistant bacteria in 2012 so as to provide guidance for prevention and control of the multidrug‐resistant bacteria infections .METHODS The bacteria that were isolated from the clinical specimens submitted from Jan 2012 to Dec 2012 were identified by using Walk A‐way40 SI bacteria analyzer ,the drug susceptibility testing was carried out ,and the statistical analysis was per‐formed by using WHONET software .RESULTS A total of 3 148 strains of pathogens have been isolated from the 10 826 clinical specimens in 2012 ,of which 15 .60% (491 strains) were the multidrug‐resistant bacteria ,including 363 (73 .93% ) strains of gram‐negative bacteria and 128 (26 .07% ) strains of gram‐positive bacteria;the A cineto‐bacterbaumannii,Klebsiellapneumoniae,Escherichiacoli,Pseudomonasaeruginosa,andStaphylococcusaureus ranked the top five species of pathogens ,accounting for 18 .33% ,17 .11% ,16 .50% ,10 .59% ,and 8 .56% ,re‐spectively .As for the clinical distribution of the multidrug‐resistant bacteria ,26 .68% were isolated from the neu‐rosurgery department ,18 .74% from the orthopedics departments ,10 .39% from the ICU .CONCLUSION It is very common that the clinical isolates are multidrug‐resistant ,w hich poses a serious threat to the clinical treatment of infections .It is of great significance to strengthen the surveillance of nosocomial infections and take effective pre‐vention and control measures .