中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
6期
38-40
,共3页
社区获得性肺炎%左氧氟沙星%序贯%疗效%症状%不良反应
社區穫得性肺炎%左氧氟沙星%序貫%療效%癥狀%不良反應
사구획득성폐염%좌양불사성%서관%료효%증상%불량반응
Community acquired pneumonia%Levofloxacin%Sequential%Curative effect%Symptoms%Adverse reaction
目的：分析两种左氧氟沙星用药方案治疗社区获得性肺炎（CAP）的临床疗效。方法分析我院自2012年6月～2014年6月收治的164例社区获得性肺炎的患者，随机分为对照组82例，给予静脉滴注左氧氟沙星；治疗组82例，在对照组的基础上，静脉治疗结束后，口服左氧氟沙星片。比较两组临床症状的改变、临床疗效和不良反应。结果治疗组与对照组在咳嗽、发热、肺部啰音、白细胞计数比较，差异有统计学意义（t=2.014,2.043,2.013，2.001，P＜0.05）；对照组与治疗组临床总有效率分别为80.48%(66/82),97.56%（80/82），两组比较差异有统计学意义（x2=12.231，P＜0.05）；对照组与治疗组不良反应发生率分别为4.9％（4/82）、9.8％（8/82），两组比较差异有统计学意义（x 2=1.439，P＞0.05）。结论左氧氟沙星注射液与片剂序贯疗法治疗CAP可有效改善临床症状，安全性好，同时不增加不良反应的发生率，有临床推广应用的价值。
目的：分析兩種左氧氟沙星用藥方案治療社區穫得性肺炎（CAP）的臨床療效。方法分析我院自2012年6月～2014年6月收治的164例社區穫得性肺炎的患者，隨機分為對照組82例，給予靜脈滴註左氧氟沙星；治療組82例，在對照組的基礎上，靜脈治療結束後，口服左氧氟沙星片。比較兩組臨床癥狀的改變、臨床療效和不良反應。結果治療組與對照組在咳嗽、髮熱、肺部啰音、白細胞計數比較，差異有統計學意義（t=2.014,2.043,2.013，2.001，P＜0.05）；對照組與治療組臨床總有效率分彆為80.48%(66/82),97.56%（80/82），兩組比較差異有統計學意義（x2=12.231，P＜0.05）；對照組與治療組不良反應髮生率分彆為4.9％（4/82）、9.8％（8/82），兩組比較差異有統計學意義（x 2=1.439，P＞0.05）。結論左氧氟沙星註射液與片劑序貫療法治療CAP可有效改善臨床癥狀，安全性好，同時不增加不良反應的髮生率，有臨床推廣應用的價值。
목적：분석량충좌양불사성용약방안치료사구획득성폐염（CAP）적림상료효。방법분석아원자2012년6월～2014년6월수치적164례사구획득성폐염적환자，수궤분위대조조82례，급여정맥적주좌양불사성；치료조82례，재대조조적기출상，정맥치료결속후，구복좌양불사성편。비교량조림상증상적개변、림상료효화불량반응。결과치료조여대조조재해수、발열、폐부라음、백세포계수비교，차이유통계학의의（t=2.014,2.043,2.013，2.001，P＜0.05）；대조조여치료조림상총유효솔분별위80.48%(66/82),97.56%（80/82），량조비교차이유통계학의의（x2=12.231，P＜0.05）；대조조여치료조불량반응발생솔분별위4.9％（4/82）、9.8％（8/82），량조비교차이유통계학의의（x 2=1.439，P＞0.05）。결론좌양불사성주사액여편제서관요법치료CAP가유효개선림상증상，안전성호，동시불증가불량반응적발생솔，유림상추엄응용적개치。
Objective To analyze the curative effect of two kinds of levofloxacin regimen in the treatment of community acquired pneumoni(CAP). Methods 164 cases of community acquired pneumonia in our hospital from 2012 June to 2014 June were analyzed and randomly divided into the control group(82 cases),which was given intravenous levofloxacin,and the treatment group(82 cases)which was given oral Levofloxacin Tablets on the basis of the control group after intravenous treatment.The clinical symptoms change, clinical efficacy and adverse reactions of two groups were compared with each other. Results There were statistically significant differences between the two groups in the cough, fever, pulmonary rales, leucocyte count(t=2.014,2.043,2.013, 2.001;P<0.05);The total clinical effective rates between the control group and the treatment group were 80.48%(66/82), 97.56%(80/82),the difference was statistical significance (x2=12.231,P<0.05);The incidences of adverse reactions were 4.9%(4/82), 9.8%(8/82), there was significant difference between the two groups (x2=1.439,P > 0.05). Conclusion The clinical curative effect of sequential therapy of levofloxacin of injection and tablets for CAP, can improve the clinical symptoms, has good safety.It does not increase the incidence rate of adverse reaction, has clinical application value.
