CAJ | 학술논문

目的：探讨我院NICU院内感染肺炎克雷伯菌败血症的临床特点及药敏情况，为早期诊断合理治疗提供依据。方法对我院NICU 11例确诊为院内感染肺炎克雷伯菌败血症的新生儿资料进行临床特点及药敏结果的回顾性分析。结果肺炎克雷伯菌败血症多见于早产儿，病情进展快，易造成多脏器功能损害；以产ESBLS菌株为主，耐药性强，对一般常用抗生素不敏感。结论新生儿尤其早产儿院内感染应重视肺炎克雷伯菌败血症，首选碳青霉烯类如亚胺培南及美罗培南治疗，以尽早控制疾病发展，降低病死率。
목적：탐토아원NICU원내감염폐염극뢰백균패혈증적림상특점급약민정황，위조기진단합리치료제공의거。방법대아원NICU 11례학진위원내감염폐염극뢰백균패혈증적신생인자료진행림상특점급약민결과적회고성분석。결과폐염극뢰백균패혈증다견우조산인，병정진전쾌，역조성다장기공능손해；이산ESBLS균주위주，내약성강，대일반상용항생소불민감。결론신생인우기조산인원내감염응중시폐염극뢰백균패혈증，수선탄청매희류여아알배남급미라배남치료，이진조공제질병발전，강저병사솔。
Objective To study the clinical effect and the drug sensitivity of nosocomial neonatal septicemia caused by klebsiella pneumonia in neonatal intensive care unit (NICU) to provide evidence for early diagnosis and reasonable treatment. Methods To retrospectively analyze the clinical effect and the drug sensitivity of 11 cases of nosocomial neonatal septicemia caused by klebsiella pneumonia in NICU of our hospital. Results Septicemia caused by klebsiella pneumonia which was more common in premature infants was easy to cause multiple organ damage, to malnly produce ESBLS, has strong drug resistance and was insensitive to the commonly used antibiotics. Conclusion Nosocomial neonatal specially premature infants should to emphasize the septicemia which caused by klebsiella pneumonia, to treat with carbapenems such as imipenem and meropenem, to control the disease development and to reduce the fatality rate.