中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
10期
2216-2218
,共3页
莫西沙星%呼吸道感染%老年患者%安全有效
莫西沙星%呼吸道感染%老年患者%安全有效
막서사성%호흡도감염%노년환자%안전유효
Moxifloxacin%Respiratory tract infection%Elderly patient%Safety and effectiveness
目的：分析莫西沙星治疗老年呼吸道感染的有效性与安全性，为提高该类患者的临床疗效提供参考依据。方法选取医院2012年1月－2013年12月收治的236例老年呼吸道感染患者，将其随机平分为莫西沙星治疗组（A组）和左氧氟沙星治疗组（B组），各118例，分别使用莫西沙星与左氧氟沙星治疗，对比分析两组患者的临床疗效、不良反应发生率以及治疗前后病原学检查结果；采用SPSS19．0软件对数据进行统计分析。结果 A组患者治疗有效率为94．9％，明显高于 B组的80．5％，两组比较差异有统计学意义（ P＜0．05）；A 组细菌清除率为91．2％，明显高于B组的69．7％，两组比较差异有统计学意义（ P＜0．05）；A、B两组患者不良反应发生率分别为6．78％和5．93％，差异无统计学意义，且症状均较轻微，经进一步治疗后即可痊愈。结论莫西沙星治疗老年呼吸道感染患者不良反应发生率低，临床见效快，且疗效显著，可缩短患者住院时间、节省就医成本。
目的：分析莫西沙星治療老年呼吸道感染的有效性與安全性，為提高該類患者的臨床療效提供參攷依據。方法選取醫院2012年1月－2013年12月收治的236例老年呼吸道感染患者，將其隨機平分為莫西沙星治療組（A組）和左氧氟沙星治療組（B組），各118例，分彆使用莫西沙星與左氧氟沙星治療，對比分析兩組患者的臨床療效、不良反應髮生率以及治療前後病原學檢查結果；採用SPSS19．0軟件對數據進行統計分析。結果 A組患者治療有效率為94．9％，明顯高于 B組的80．5％，兩組比較差異有統計學意義（ P＜0．05）；A 組細菌清除率為91．2％，明顯高于B組的69．7％，兩組比較差異有統計學意義（ P＜0．05）；A、B兩組患者不良反應髮生率分彆為6．78％和5．93％，差異無統計學意義，且癥狀均較輕微，經進一步治療後即可痊愈。結論莫西沙星治療老年呼吸道感染患者不良反應髮生率低，臨床見效快，且療效顯著，可縮短患者住院時間、節省就醫成本。
목적：분석막서사성치료노년호흡도감염적유효성여안전성，위제고해류환자적림상료효제공삼고의거。방법선취의원2012년1월－2013년12월수치적236례노년호흡도감염환자，장기수궤평분위막서사성치료조（A조）화좌양불사성치료조（B조），각118례，분별사용막서사성여좌양불사성치료，대비분석량조환자적림상료효、불량반응발생솔이급치료전후병원학검사결과；채용SPSS19．0연건대수거진행통계분석。결과 A조환자치료유효솔위94．9％，명현고우 B조적80．5％，량조비교차이유통계학의의（ P＜0．05）；A 조세균청제솔위91．2％，명현고우B조적69．7％，량조비교차이유통계학의의（ P＜0．05）；A、B량조환자불량반응발생솔분별위6．78％화5．93％，차이무통계학의의，차증상균교경미，경진일보치료후즉가전유。결론막서사성치료노년호흡도감염환자불량반응발생솔저，림상견효쾌，차료효현저，가축단환자주원시간、절성취의성본。
OBJECTIVE To observe the effectiveness and safety of moxifloxacin in treatment of the elderly patients with respiratory tract infections so as to improve the clinical efficacy in treatment of such group of patients . METHODS A total of 236 elderly patients with respiratory tract infections who were treated in the hospital from Jan 2012 to Dec 2013 were enrolled in the study and randomly divided into the moxifloxacin treatment group (the group A) and the levofloxacin treatment group (the group B) ,with 118 cases in each;the group A was treated with moxifloxacin ,while the group B was given the levofloxacin .The clinical efficacies ,incidence of adverse reac‐tions ,and results of etiological examination were observed and compared between the two groups ,and the statisti‐cal analysis was performed with the use of SPSS19 .0 software .RESULTS The effective rate of treatment of the group A was 94 .9% ,significantly higher than 80 .5% of the group B(P<0 .05);the bacterial clearance rate of the group A was 91 .2% ,significantly higher than 69 .7% of the group B(P<0 .05) .The incidence of adverse re‐actions was 6 .78% in the group A ,5 .93% in the group B ,and there was no significant difference;all the patients had mild symptoms and were cured through further treatment .CONCLUSION Moxifloxacin can achieve significant clinical efficacy in treatment of the elderly patients with respiratory tract infections ,shorten the length of hospital stay ,and save the medical cost ,with the incidence of adverse reactions low .
