CAJ | 학술논문

目的：探讨聚维酮碘稀释液在预防坏疽性阑尾炎伴穿孔术后感染中的效果及安全性，为临床治疗提供参考。方法选取2012年6月－2014年2月医院收治的93例阑尾炎患者作为研究试验对象，根据入院时间先后将患者分成观察组47例和对照组46例，观察组患者术后采用聚维酮碘进行冲洗，对照组患者常规使用生理盐水冲洗，对比分析两组腹腔及切口感染情况；使用SPSS13．0软件进行统计分析。结果观察组患者术后感染率为2．13％，对照组为13．04％，两组比较差异有统计学意义（ P＜0．05）；观察组患者切口愈合整齐，甲级愈合率为68．08％，对照组患者甲级愈合率为50．00％，两组比较差异有统计学意义（u＝2．0859，P＜0．05）；患者术后体温上升，但体温恢复时间相差不大，两组比较差异无统计学意义，但观察组患者肛门排气时间和住院时间明显低于对照组患者，恢复较好，两组比较差异有统计学意义（P＜0．05）；两组患者术后均无任何不良反应发生，安全性高，差异无统计学意义。结论聚维酮碘稀释液在预防坏疽性阑尾炎伴穿孔术后腹腔及切口感染中疗效较好，患者术后感染率较低，切口愈合较好，无不良反应发生，安全性高。
목적：탐토취유동전희석액재예방배저성란미염반천공술후감염중적효과급안전성，위림상치료제공삼고。방법선취2012년6월－2014년2월의원수치적93례란미염환자작위연구시험대상，근거입원시간선후장환자분성관찰조47례화대조조46례，관찰조환자술후채용취유동전진행충세，대조조환자상규사용생리염수충세，대비분석량조복강급절구감염정황；사용SPSS13．0연건진행통계분석。결과관찰조환자술후감염솔위2．13％，대조조위13．04％，량조비교차이유통계학의의（ P＜0．05）；관찰조환자절구유합정제，갑급유합솔위68．08％，대조조환자갑급유합솔위50．00％，량조비교차이유통계학의의（u＝2．0859，P＜0．05）；환자술후체온상승，단체온회복시간상차불대，량조비교차이무통계학의의，단관찰조환자항문배기시간화주원시간명현저우대조조환자，회복교호，량조비교차이유통계학의의（P＜0．05）；량조환자술후균무임하불량반응발생，안전성고，차이무통계학의의。결론취유동전희석액재예방배저성란미염반천공술후복강급절구감염중료효교호，환자술후감염솔교저，절구유합교호，무불량반응발생，안전성고。
OBJECTIVE To explore the efficacy and safety of povidone‐iodine dilutions in prevention of postoperative complicated infections in the gangrenous appendicitis patients undergoing perforation so as to provide guidance for the clinical treatment .METHODS A total of 93 appendicitis patients who were treated in the hospital from Jun 2012 to Feb 2014 were recruited as the study objects and divided into the observation group with 47 cases and the con‐trol group with 46 cases according to the order of admission .The observation group was treated with povidone‐io‐dine for irrigation after the surgery ,while the control group was treated with conventional normal saline for irriga‐tion ;the incidence rates of abdominal and incision infections were observed and compared between the two groups , and the statistical analysis was performed with the use of SPSS13 .0 software .RESULTS The incidence of postoper‐ative infections was 2 .13% in the observation group ,13 .04% in the control group ,and there was significant difference between the two groups (P<0 .05) .The patients of the observation group had neat incision healing with the grade A incision healing rate of 68 .08% ,significantly higher than 50 .00% of the patients of the control group (u=2 .0859 ,P<0 .05) .The body temperatures of the patients were elevated after the surgery ,however ,the re‐covery time of the body temperatures did not vary significantly ,the anal exhaust time and length of hospital stay of the observation group were significantly shorter than those of the control group ,with the recovery good(P<0 .05) .The postoperative adverse reactions occurred in neither of the two groups .CONCLUSION Povidone‐iodine dilutions can achieve significant effect on prevention of postoperative abdominal and incision infections in the gan‐grenous appendicitis patients undergoing perforation ,the incidence of postoperative infections is low ,the incision healing is good ,the adverse reactions do not occur ,and the safety is high in the hospital .