中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
15期
2371-2375
,共5页
组织构建%组织工程%颈动脉%三维CT%影像解剖%钙化%国家自然科学基金
組織構建%組織工程%頸動脈%三維CT%影像解剖%鈣化%國傢自然科學基金
조직구건%조직공정%경동맥%삼유CT%영상해부%개화%국가자연과학기금
Subject headings:Carotid Arteries%Imaging,Three-Dimensional%Dissection
背景：颈内动脉虹吸部结构复杂，由于颅底骨结构的遮挡，二维影像学观察存在一定的困难。数字减影血管造影(DSA)有利于显示颈内动脉的行程，但缺乏解剖标志。CT三维成像有利于显示颈内动脉管壁、壁内外结构与测量，为相关研究提供了有效的新手段。<br> 目的：明确颈内动脉虹吸部相关形态及钙化分布特点，为相关医学临床与基础研究提供客观依据。<br> 方法：选择50岁以上行头颈CT血管造影检查无明显病变或变异者206例作为研究对象，分为无钙化组70例、钙化组136例。在图像工作站上重建颈内动脉虹吸部，观察其分型(根据虹吸部的解剖形态分为“U”型，“V”型，“C”型，“S”型)与钙化分布，测量C4、C5弯曲的折角及管腔内径。<br> 结果与结论：颈内动脉虹吸部无钙化组70例，年龄为(59.17±10.27)岁，虹吸部“U”型占35.7%、“V”型30.7%、“C”型占27.2%、“S”型占6.4%，其中两侧分型相同者占33.3%(25/70例)；管腔内径为(4.92±0.63) mm，虹吸部C4、C5折角分别为(87.23±16.66)°、(49.21±16.01)°；钙化组136例，年龄为(67.39±9.32)岁，虹吸部“U”型占41.5%、“V”型33.1%、“C”型占24.3%、“S”型占1.1%，其中两侧分型相同者占43.4%(59/136例)；管腔内径为(4.90±0.44) mm，虹吸部C4、C5折角分别为(84.44±17.20)°、(52.57±14.16)°。统计学分析两组间年龄、S型分型有显著性差异(P <0.05)，虹吸部管腔内径、C4、C5段折角无显著性差异(P >0.05)。无钙化组及钙化组C4折角内、外弯区钙化分别占13.60%、19.01%；C5折角占27.34%、16.52%；C6段占9.94%、13.60%。结果表明，颈内虹吸部形态以“U”、“V”、“C”型多见，两侧分型不同超过50%。管壁钙化以C5折角内弯区最多、C4折角外弯区其次，钙化随年龄增大而发生率增多，其中钙化虹吸部S型发生率较低，钙化与管腔、折角大小无明显关系。
揹景：頸內動脈虹吸部結構複雜，由于顱底骨結構的遮擋，二維影像學觀察存在一定的睏難。數字減影血管造影(DSA)有利于顯示頸內動脈的行程，但缺乏解剖標誌。CT三維成像有利于顯示頸內動脈管壁、壁內外結構與測量，為相關研究提供瞭有效的新手段。<br> 目的：明確頸內動脈虹吸部相關形態及鈣化分佈特點，為相關醫學臨床與基礎研究提供客觀依據。<br> 方法：選擇50歲以上行頭頸CT血管造影檢查無明顯病變或變異者206例作為研究對象，分為無鈣化組70例、鈣化組136例。在圖像工作站上重建頸內動脈虹吸部，觀察其分型(根據虹吸部的解剖形態分為“U”型，“V”型，“C”型，“S”型)與鈣化分佈，測量C4、C5彎麯的摺角及管腔內徑。<br> 結果與結論：頸內動脈虹吸部無鈣化組70例，年齡為(59.17±10.27)歲，虹吸部“U”型佔35.7%、“V”型30.7%、“C”型佔27.2%、“S”型佔6.4%，其中兩側分型相同者佔33.3%(25/70例)；管腔內徑為(4.92±0.63) mm，虹吸部C4、C5摺角分彆為(87.23±16.66)°、(49.21±16.01)°；鈣化組136例，年齡為(67.39±9.32)歲，虹吸部“U”型佔41.5%、“V”型33.1%、“C”型佔24.3%、“S”型佔1.1%，其中兩側分型相同者佔43.4%(59/136例)；管腔內徑為(4.90±0.44) mm，虹吸部C4、C5摺角分彆為(84.44±17.20)°、(52.57±14.16)°。統計學分析兩組間年齡、S型分型有顯著性差異(P <0.05)，虹吸部管腔內徑、C4、C5段摺角無顯著性差異(P >0.05)。無鈣化組及鈣化組C4摺角內、外彎區鈣化分彆佔13.60%、19.01%；C5摺角佔27.34%、16.52%；C6段佔9.94%、13.60%。結果錶明，頸內虹吸部形態以“U”、“V”、“C”型多見，兩側分型不同超過50%。管壁鈣化以C5摺角內彎區最多、C4摺角外彎區其次，鈣化隨年齡增大而髮生率增多，其中鈣化虹吸部S型髮生率較低，鈣化與管腔、摺角大小無明顯關繫。
배경：경내동맥홍흡부결구복잡，유우로저골결구적차당，이유영상학관찰존재일정적곤난。수자감영혈관조영(DSA)유리우현시경내동맥적행정，단결핍해부표지。CT삼유성상유리우현시경내동맥관벽、벽내외결구여측량，위상관연구제공료유효적신수단。<br> 목적：명학경내동맥홍흡부상관형태급개화분포특점，위상관의학림상여기출연구제공객관의거。<br> 방법：선택50세이상행두경CT혈관조영검사무명현병변혹변이자206례작위연구대상，분위무개화조70례、개화조136례。재도상공작참상중건경내동맥홍흡부，관찰기분형(근거홍흡부적해부형태분위“U”형，“V”형，“C”형，“S”형)여개화분포，측량C4、C5만곡적절각급관강내경。<br> 결과여결론：경내동맥홍흡부무개화조70례，년령위(59.17±10.27)세，홍흡부“U”형점35.7%、“V”형30.7%、“C”형점27.2%、“S”형점6.4%，기중량측분형상동자점33.3%(25/70례)；관강내경위(4.92±0.63) mm，홍흡부C4、C5절각분별위(87.23±16.66)°、(49.21±16.01)°；개화조136례，년령위(67.39±9.32)세，홍흡부“U”형점41.5%、“V”형33.1%、“C”형점24.3%、“S”형점1.1%，기중량측분형상동자점43.4%(59/136례)；관강내경위(4.90±0.44) mm，홍흡부C4、C5절각분별위(84.44±17.20)°、(52.57±14.16)°。통계학분석량조간년령、S형분형유현저성차이(P <0.05)，홍흡부관강내경、C4、C5단절각무현저성차이(P >0.05)。무개화조급개화조C4절각내、외만구개화분별점13.60%、19.01%；C5절각점27.34%、16.52%；C6단점9.94%、13.60%。결과표명，경내홍흡부형태이“U”、“V”、“C”형다견，량측분형불동초과50%。관벽개화이C5절각내만구최다、C4절각외만구기차，개화수년령증대이발생솔증다，기중개화홍흡부S형발생솔교저，개화여관강、절각대소무명현관계。
BACKGROUND:The carotid siphon has a complex structure, which is difficult for two-dimensional imaging observation due to shelter from the basicranial bone. Digital subtraction angiography is conducive to display the course of carotid siphon, but there is a lack of anatomical landmarks. Three-dimensional CT imaging is beneficial to show the structure of carotid siphon and have its measurement, which provides a new and effective means in relevant studies. <br> OBJECTIVE:To clarify the morphology and calcification distribution of the carotid siphon, thereby providing an objective basis for relevant clinical and basic research. <br> METHODS: A total of 206 patients, over 50 years old, with no lesions or variation under head and neck CT angiography were selected and divided into non-calcification group (n=70) and calcification group (n=136). The carotid siphon was reconstructed on the imaging workstation to observe the classification (“U”, “V”, “C” and “S” types) and calcification distribution, the bending angles of C4 and C5 segments as wel as lumen diameter were measured. <br> RESULTS AND CONCLUSION:The 70 patients in the non-calcification group were at a mean age of (59.17±10.27) years, and the “U” type accounted for 35.7%, “V” type for 30.7%, “C” type for 27.2%, and “S” type for 6.4%; Among them, 33.3% patients (25/70) had the same type at both sides; the lumen diameter was (4.92±0.63) mm, and the blending angles of C4 and C5 were (87.23±16.66)° and (49.21±16.01)°. In the calcification group, the mean age was (67.39±9.32) years, and there were 41.5% of “U” type, 33.1% of “V” type, 24.3% of “C” type, 1.1% of 24.3%, and among the 136 patients, 43.4% (59/136) showed the same type at both sides; the lumen diameter was (4.90±0.44) mm, and the blending angles of C4 and C5 segments were (84.44±17.20)° and (52.57±14.16)°. There were significant differences in age and “S” type between the two groups (P < 0.05), but no statistical difference in the lumen diameter and blending angles of C4 and C5 (P > 0.05). In the calcification group, the calcification percentage of inwardly and outwardly curved regions was 13.60% and 19.01% for C4, 27.34% and 16.52% for C5, 9.94% and 13.60% for C6. The morphology of the carotid siphon is mostly seen as “U”, “V”, “C” types, and over 50% types are different at both sides. Calcification of the lumen wal is seen most in the inwardly curved region of C5 segment, folowed by the outwardly curved region of C4 segment. The incidence of calcification is increased with age, which is lower in the S-type carotid siphon. The lumen diameter and blending angle of the carotid siphon show no correlation with calcifications.
