食品研究与开发
食品研究與開髮
식품연구여개발
FOOD RESEARCH AND CEVELOPMENT
2015年
7期
118-121,122
,共5页
翟广玉%颜子童%渠文涛%郜蕾%千依琳
翟廣玉%顏子童%渠文濤%郜蕾%韆依琳
적엄옥%안자동%거문도%고뢰%천의림
槲皮素%健康%抗癌%自由基%清除
槲皮素%健康%抗癌%自由基%清除
곡피소%건강%항암%자유기%청제
quercetin%health%anticancer%free radical%scavenging
槲皮素属于生物黄酮类,广泛分布于人们的食用植物中。槲皮素具有多方面的生物活性。槲皮素作为一个对人们健康非常有益的天然化合物,近几年来引起了国内外研究者的广泛的兴趣,研究论文呈直线上升趋势。自由基可导致细胞损伤,是产生许多疾病的主要原因。槲皮素主要的功能是抗氧化,清除自由基。槲皮素能使血管舒张作用,改善内皮细胞、加强氧化应激;抑制低密度脂蛋白氧化;减少粘附分子和其他炎症标记物;防止神经元氧化和炎性损伤血管内皮功能。槲皮素还可通过清除超氧阴离子、羟自由基及与自由基相关酶作用对抗氧化应激过程,从而保护心肌细胞。大量的证据表明,多食用含有槲皮素的水果和蔬菜可减少心血管疾病。槲皮素可以阻止潜在的致癌物成为最终的致癌物。研究表明槲皮素能有效地阻止环境中致癌物在人体内的活化;能加快致癌物在人体内的降解,并促进其排出;能诱导肿瘤细胞的分化,促进肿瘤细胞的凋亡。槲皮素对癌症防治具有重要作用。
槲皮素屬于生物黃酮類,廣汎分佈于人們的食用植物中。槲皮素具有多方麵的生物活性。槲皮素作為一箇對人們健康非常有益的天然化閤物,近幾年來引起瞭國內外研究者的廣汎的興趣,研究論文呈直線上升趨勢。自由基可導緻細胞損傷,是產生許多疾病的主要原因。槲皮素主要的功能是抗氧化,清除自由基。槲皮素能使血管舒張作用,改善內皮細胞、加彊氧化應激;抑製低密度脂蛋白氧化;減少粘附分子和其他炎癥標記物;防止神經元氧化和炎性損傷血管內皮功能。槲皮素還可通過清除超氧陰離子、羥自由基及與自由基相關酶作用對抗氧化應激過程,從而保護心肌細胞。大量的證據錶明,多食用含有槲皮素的水果和蔬菜可減少心血管疾病。槲皮素可以阻止潛在的緻癌物成為最終的緻癌物。研究錶明槲皮素能有效地阻止環境中緻癌物在人體內的活化;能加快緻癌物在人體內的降解,併促進其排齣;能誘導腫瘤細胞的分化,促進腫瘤細胞的凋亡。槲皮素對癌癥防治具有重要作用。
곡피소속우생물황동류,엄범분포우인문적식용식물중。곡피소구유다방면적생물활성。곡피소작위일개대인문건강비상유익적천연화합물,근궤년래인기료국내외연구자적엄범적흥취,연구논문정직선상승추세。자유기가도치세포손상,시산생허다질병적주요원인。곡피소주요적공능시항양화,청제자유기。곡피소능사혈관서장작용,개선내피세포、가강양화응격;억제저밀도지단백양화;감소점부분자화기타염증표기물;방지신경원양화화염성손상혈관내피공능。곡피소환가통과청제초양음리자、간자유기급여자유기상관매작용대항양화응격과정,종이보호심기세포。대량적증거표명,다식용함유곡피소적수과화소채가감소심혈관질병。곡피소가이조지잠재적치암물성위최종적치암물。연구표명곡피소능유효지조지배경중치암물재인체내적활화;능가쾌치암물재인체내적강해,병촉진기배출;능유도종류세포적분화,촉진종류세포적조망。곡피소대암증방치구유중요작용。
Belonging to bio-flavonoids quercetin , are widely distributed in food plants. Quercetin has a wide range of biological activities. Quercetin as a natural compound that is very beneficial to people's health , attracted the interest of researchers widely at home and abroad in recent years , research paper on a rising trend. Free radicals can cause cell damage, was the main cause of many diseases. Quercetin main function is antioxidant, scavenging free radicals. Vasodilation effect of quercetin, improved, enhanced oxidative stress in endothelial cells;inhibit low density lipoprotein oxidation;reduce adhesion molecules and other inflammatory markers;preventing neuronal oxidative and inflammatory injury of vascular endothelial function. Quercetin can also scavenge superoxide anion, hydroxyl free radical and enzyme effects against oxidative stress and free radical processes, thereby protecting myocardial cells. Abundant evidence showed that consumption of fruits and vegetables contain quercetin can reduce cardiovascular disease. Quercetin can prevent potential carcinogens into the ultimate carcinogen. Studies had shown that quercetin can effectively prevent the activation of carcinogens in the environment in the human body;can accelerate the degradation of carcinogen in humans , and promoting their discharge;can induce differentiation of tumor cells , promoting apoptosis of tumor cells. An important role of quercetin on cancer prevention and treatment.