CAJ | 학술논문

循环肿瘤细胞（CTC）是非小细胞肺癌（NSCLC）发生复发转移的重要原因。随着检测技术的不断发展，近期研究结果提示，CTC 水平不仅可以用来判断肿瘤临床分期、评估患者预后及治疗反应，还可以用于早期 NSCLC 的风险评估。另外，作为一种非侵入性的“液体活检”，CTC 检测能反映原发肿瘤的分子生物学及遗传学特征，有助于患者获得最佳的个体化治疗。
순배종류세포（CTC）시비소세포폐암（NSCLC）발생복발전이적중요원인。수착검측기술적불단발전，근기연구결과제시，CTC 수평불부가이용래판단종류림상분기、평고환자예후급치료반응，환가이용우조기 NSCLC 적풍험평고。령외，작위일충비침입성적“액체활검”，CTC 검측능반영원발종류적분자생물학급유전학특정，유조우환자획득최가적개체화치료。
Circulating tumor cells(CTCs)are essential for establishing metastasis and recurrence in non-small cell lung cancer(NSCLC). With the development of detection technique,results from recent studies suggest that CTC level could be a supplement for TNM staging system and a prediction marker of prognosis and therapeutic efficacy,and even could be applied for risk assessment of early NSCLC. Furthermore,as a non-invasive"liquid biopsy",detection of CTC can reflect the molecular biology and genetics characteristics of the primary tumor,and subsequently assist in selecting an optimal individualized treatment.