CAJ | 학술논문

目的通过分析垂体腺瘤患者的MRI-T1WI图像,探讨垂体后叶亮点(PPBS)的出现率、位置分布及其影响因素.方法选择南京军区福州总医院神经外科自2012年9月至2014年9月收治的垂体腺瘤患者123例,所有患者术前行MRI SE序列的T1WI、T2WI矢状位、冠状位、轴位平扫和增强扫描.观察垂体腺瘤的形态、PPBS的位置与信号,比较不同形态垂体腺瘤患者的PPBS以及出现PPBS与未出现PPBS垂体腺瘤患者的临床资料.结果本组患者中出现PPBS者98例(79.7％),未出现PPBS者25例(20.3％);垂体腺瘤中沙漏型43例、筒型63例、楔型17例;统计结果显示沙漏型垂体腺瘤患者PPBS出现率较筒型高,筒型和楔型垂体腺瘤患者PPBS与脑桥的信号强度比较沙漏型高,差异有统计学意义(P＜0.05);未出现PPBS组垂体腺瘤患者肿瘤高度、体积均大于出现PPBS组,差异有统计学意义(P＜0.05).出现PPBS与未出现PPBS垂体腺瘤患者的腺瘤形态分布不同,差异有统计学意义(P＜0.05).结论 MRI图像能够较好地显示PPBS,且PPBS的出现与垂体腺瘤的形态、体积、高度有关.
목적 통과분석수체선류환자적MRI-T1WI도상,탐토수체후협량점(PPBS)적출현솔、위치분포급기영향인소.방법 선택남경군구복주총의원신경외과자2012년9월지2014년9월수치적수체선류환자123례,소유환자술전행MRI SE서렬적T1WI、T2WI시상위、관상위、축위평소화증강소묘.관찰수체선류적형태、PPBS적위치여신호,비교불동형태수체선류환자적PPBS이급출현PPBS여미출현PPBS수체선류환자적림상자료.결과 본조환자중출현PPBS자98례(79.7％),미출현PPBS자25례(20.3％);수체선류중사루형43례、통형63례、설형17례;통계결과현시사루형수체선류환자PPBS출현솔교통형고,통형화설형수체선류환자PPBS여뇌교적신호강도비교사루형고,차이유통계학의의(P＜0.05);미출현PPBS조수체선류환자종류고도、체적균대우출현PPBS조,차이유통계학의의(P＜0.05).출현PPBS여미출현PPBS수체선류환자적선류형태분포불동,차이유통계학의의(P＜0.05).결론 MRI도상능구교호지현시PPBS,차PPBS적출현여수체선류적형태、체적、고도유관.
Objective To analyze the occurrence and location of posterior pituitary bright spot (PPBS) and its influence factors by analyzing the magnetic resonance T1-weighted imaging (T1WI) in patients with pituitary adenoma.Methods One hundred and twenty-three patients with pituitary adenoma,admitted to our hospital from September 2012 to September 2014,were collected in our study.All patients were performed T1WI and T2WI sagittal,coronal and axial scan and enhanced scan at SE sequence before operation.The occurrence and location of PPBS of the pituitary gland were observed;the clinical data of these patients from PPBS-visible group and PPBS-non-visible group were analyzed and compared.Re.sults Of the 123 patients,the PPBS-visible group included 98 patients (79.7％) and the PPBS-non-visible group included 25 patients (20.3％).The adenoma shapes were classified into hourglass-type (n=43),barrel-type (n=63) and wedge-type (n=17).The occurrencerateofPPBSin barrel-type patients was significantly lower than hourglass-type patients (P＜0.05);the signal intensity ratio of PPBS and pons in barrel-type patients and wedge-type patients was significantly higher than that in the hourglass-type patients (P＜0.05).Adenoma volume and height of the PPBS-visible group was significantly smaller than those in the PPBS-non-visible group (P＜0.05).The distribution of different adenoma types was significantly different between patients from PPBS-visible group and PPBS-non-visible group (P＜0.05).Conclusion The posterior lobe of pituitary could be displayed satisfactorily at T1WI,and appearance of PPBS is related to the morphology,volume and height of pituitary adenoma.