CAJ | 학술논문

目的探讨应用PRGD复合神经导管桥接修复上肢粗大周围神经缺损的疗效. 方法 2011年12月-2014年8月,应用PRGD复合神经导管桥接修复上肢粗大周围神经缺损的患者19例,其中正中神经和桡神经各6例,尺神经7例.术后定期随访,行感觉、运动功能、高频超声及肌电图检查评估. 结果 19例患者术后均获随访,随访时间12～32(21.75±6.86)个月,根据英国医学研究会感觉、运动评价标准进行综合评价,优7例,良7例,可3例,差2例,结果优良率达73.7％. 结论应用PRGD复合神经导管桥接修复上肢粗大周围神经缺损具有良好的疗效,为其进一步临床应用奠定了基础.
목적 탐토응용PRGD복합신경도관교접수복상지조대주위신경결손적료효. 방법 2011년12월-2014년8월,응용PRGD복합신경도관교접수복상지조대주위신경결손적환자19례,기중정중신경화뇨신경각6례,척신경7례.술후정기수방,행감각、운동공능、고빈초성급기전도검사평고. 결과 19례환자술후균획수방,수방시간12～32(21.75±6.86)개월,근거영국의학연구회감각、운동평개표준진행종합평개,우7례,량7례,가3례,차2례,결과우량솔체73.7％. 결론 응용PRGD복합신경도관교접수복상지조대주위신경결손구유량호적료효,위기진일보림상응용전정료기출.
Objective To explore the clinical efficacy of PRGD composite nerve conduit in the treatment of human large-diameter,critical peripheral nerve defect in upper extremity.Methods From December,2011 to August,2014,19 patients with large-diameter,critical peripheral nerve defect in upper extremity were treated with PRGD composite nerve conduit.The patients were followeded-up periodically.The sensory and motor function recovery,high frequency ultrasound,and EMG were employed to assess the efficacy.Results The patients were followed up for an average time of 12-32 months(mean 21.75 ± 6.86 months),sensory and motor function recovered excellent in 7 patients,satisfactory in 7 patients,tolerable in 3 patients and no improvement in 2 patients were obtained according to the peripheral nerve function assessment standard built by British medical research council,the rate excellent and satisfactory results was 73.7％.Conclusion It is clinically promising to use PRGD composite nerve conduit to repair large-diameter,critical peripheral nerve defect in upper extremity,thus laying a foundation for its further application in clinical practice.