CAJ | 학술논문

为系统研究DHV在脑组织引起的病理变化随时间的发展变化规律，通过人工感染雏鸭DHV的方法建立DHV的疾病病理模型，运用常规病理技术、组织中自由基的测定等方法，探索DHV感染时间的发展，脑组织病变和感染时间之间的关联度以及组织生化指标和脑组织病变之间的关联度。结果显示，试验组雏鸭大脑于攻毒后不同时间内出现不同程度的病理变化，脑组织中NO、MDA含量随时间变化一致。试验得出：NO在雏鸭病毒性肝炎的发生、发展的过程中发挥了重要作用，可能是雏鸭出现神经症状和脑组织病变的重要原因之一。
위계통연구DHV재뇌조직인기적병리변화수시간적발전변화규률，통과인공감염추압DHV적방법건립DHV적질병병리모형，운용상규병리기술、조직중자유기적측정등방법，탐색DHV감염시간적발전，뇌조직병변화감염시간지간적관련도이급조직생화지표화뇌조직병변지간적관련도。결과현시，시험조추압대뇌우공독후불동시간내출현불동정도적병리변화，뇌조직중NO、MDA함량수시간변화일치。시험득출：NO재추압병독성간염적발생、발전적과정중발휘료중요작용，가능시추압출현신경증상화뇌조직병변적중요원인지일。
DHV for systematic study of pathological changes in the brain caused by the variation with time of development , build models of disease pathology by the methods of artificial infection DHV DHV ducklings , the use of conventional pathology techniques , methods, and other organizations in the determination of free radicals, explore DHV infection development time, the correlation of the organization and the associated brain lesions and biochemical indices between brain lesions and the time between infection .The results showed that the experimental group of ducklings pathological changes in the brain in different degrees at different times appear after challenge , Brain tissue NO, MDA content changes over time is consistent. Test results : NO plays an important role in the incidence of viral hepatitis ducklings and the process of development, may be one important reason for Ducklings neurological symptoms and brain lesions.