内蒙古医科大学学报
內矇古醫科大學學報
내몽고의과대학학보
Journal of Inner Mongolia Medical University
2015年
2期
97-101,107
,共6页
魏起友%韩巴特尔%郭占林
魏起友%韓巴特爾%郭佔林
위기우%한파특이%곽점림
非小细胞肺癌%围手术期并发症%生存率%生存因素
非小細胞肺癌%圍手術期併髮癥%生存率%生存因素
비소세포폐암%위수술기병발증%생존솔%생존인소
NSCLS%postoperative complication%survival rate%survival factor
目的：：探讨非小细胞肺癌(non-small cell lung cancer,NSCLC)病人术后1~5a生存率,及生存预后因素。方法：回顾分析内蒙古医科大学附属医院胸心外科B区2006-01~2010-12间手术治疗391例NSCLC病人的临床资料,采用门诊、电话、再次入院资料查阅等方法进行术后随访观察。选择性别、年龄、病理类型、肿瘤组织分化程度、病理分期、淋巴结清扫数、淋巴结是否转移、手术方式、术后转移、术后放疗和术后化疗等因素作为观察指标,将各观察指标量化赋值后采用,计算机SPSS 13.0软件进行数据统计,分析术后1~5 a生存率及生存预后因素,采用Kaplan-Meire法进行生存分析；采用log-rank检验和Cox多因素回归模型进行生存预后因素分析。结果：非小细胞肺癌病人术后1至5 a 生存率( survival rate,SR)分别为65.7%、57.8%、46.7%、44.3%、44.3%。中位生存时间为43.88mo。单因素分析显示年龄、淋巴结转移、淋巴结清扫数、手术方式、病理分期是术后生存期的影响因素,多因素分析显示年龄、淋巴结转移、病理分期是术后生存的主要影响因素。结论：注重非小细胞肺癌早期手术切除、彻底的淋巴结清扫可延长非小细胞肺癌病人术后的生存期。
目的：：探討非小細胞肺癌(non-small cell lung cancer,NSCLC)病人術後1~5a生存率,及生存預後因素。方法：迴顧分析內矇古醫科大學附屬醫院胸心外科B區2006-01~2010-12間手術治療391例NSCLC病人的臨床資料,採用門診、電話、再次入院資料查閱等方法進行術後隨訪觀察。選擇性彆、年齡、病理類型、腫瘤組織分化程度、病理分期、淋巴結清掃數、淋巴結是否轉移、手術方式、術後轉移、術後放療和術後化療等因素作為觀察指標,將各觀察指標量化賦值後採用,計算機SPSS 13.0軟件進行數據統計,分析術後1~5 a生存率及生存預後因素,採用Kaplan-Meire法進行生存分析；採用log-rank檢驗和Cox多因素迴歸模型進行生存預後因素分析。結果：非小細胞肺癌病人術後1至5 a 生存率( survival rate,SR)分彆為65.7%、57.8%、46.7%、44.3%、44.3%。中位生存時間為43.88mo。單因素分析顯示年齡、淋巴結轉移、淋巴結清掃數、手術方式、病理分期是術後生存期的影響因素,多因素分析顯示年齡、淋巴結轉移、病理分期是術後生存的主要影響因素。結論：註重非小細胞肺癌早期手術切除、徹底的淋巴結清掃可延長非小細胞肺癌病人術後的生存期。
목적：：탐토비소세포폐암(non-small cell lung cancer,NSCLC)병인술후1~5a생존솔,급생존예후인소。방법：회고분석내몽고의과대학부속의원흉심외과B구2006-01~2010-12간수술치료391례NSCLC병인적림상자료,채용문진、전화、재차입원자료사열등방법진행술후수방관찰。선택성별、년령、병리류형、종류조직분화정도、병리분기、림파결청소수、림파결시부전이、수술방식、술후전이、술후방료화술후화료등인소작위관찰지표,장각관찰지표양화부치후채용,계산궤SPSS 13.0연건진행수거통계,분석술후1~5 a생존솔급생존예후인소,채용Kaplan-Meire법진행생존분석；채용log-rank검험화Cox다인소회귀모형진행생존예후인소분석。결과：비소세포폐암병인술후1지5 a 생존솔( survival rate,SR)분별위65.7%、57.8%、46.7%、44.3%、44.3%。중위생존시간위43.88mo。단인소분석현시년령、림파결전이、림파결청소수、수술방식、병리분기시술후생존기적영향인소,다인소분석현시년령、림파결전이、병리분기시술후생존적주요영향인소。결론：주중비소세포폐암조기수술절제、철저적림파결청소가연장비소세포폐암병인술후적생존기。
Objective:The paper discusses postoperative complication,the survival rate from 1 year to 5 year and surviving prognosis factors on non-small cell lung cancer ( NSCLC ) . Methods:391 patients suffering from NSCLC who underwent surgery from January 2006 to December 2010 in our hospital were studied retrospectively. Through follow-up data of out-patient ward,telephone,searching of Analyzing of re-admitted data,so to summarize the incidence of postoperative complication. Possible factors were collected in the data of these patients. The factors included age,pathological type,tumor tissue differentiation, pathological stage, number of dissected lymph nodes, lymph node metastasis, operation mode, postoperative metastasis, postoperative radiotherapy and postoperative chemotherapy, etc. Analyze patients ’ survival rate from 1 to 5 year and survival prognostic factors by using the statistics software of SPSS 13. 0. Kaplan-Meire analyze on survival rate,log-rank law and Cox multi-factor regression model analysis survival of prognostic factors. Results:The incidence of postoperative complications on NSCLC was 8 . 95%. The survival rate were 65 . 7%、57 . 8%、46 . 7%、44 . 3%、44. 3%respectively in patients with NSCLC from 1 to 5 year. The median survival time was 43. 88 months. Single factor analysis showed that age, lymph node metastasis, number of dissected lymph nodes,surgical way and pathological stage were the influencing factors after operation of NSCLC. Age, pathological stage, lymph node metastasis were the major influencing factors through multi-factor analysis. Conclusion:Focusing on postoperative management on NSCLC may reduce the incidence of complications after operation. Early operation resection, radical lymph node dissection can prolong survival period after operation of NSCLC.
