CAJ | 학술논문

目的：：探讨定量分析唾液腺动态显像诊断干燥综合征的临床价值。方法：采用肘静脉“弹丸”式注射99 m TcO4-对39例干燥综合征病人和18例健康人行唾液腺动态显像。于15 min时舌下含服维生素C( Vit. C)0.1 g,利用计算机ROI(Region of interest)技术及自编软件,自动获得包含唾液腺动态图像、时间-放射性曲线及各功能参数。结果：干燥综合征组的UR、S/T、MSR明显低于正常组。 Tmin明显高于正常组,差异具有显著性,P<0.001。结论：UR、S/T、MSR及Tmin是诊断干燥综合征的灵敏指标,定量分析唾液腺动态显像对诊断因多种免疫性疾病引起的干燥综合征有较高的临床应用价值。
목적：：탐토정량분석타액선동태현상진단간조종합정적림상개치。방법：채용주정맥“탄환”식주사99 m TcO4-대39례간조종합정병인화18례건강인행타액선동태현상。우15 min시설하함복유생소C( Vit. C)0.1 g,이용계산궤ROI(Region of interest)기술급자편연건,자동획득포함타액선동태도상、시간-방사성곡선급각공능삼수。결과：간조종합정조적UR、S/T、MSR명현저우정상조。 Tmin명현고우정상조,차이구유현저성,P<0.001。결론：UR、S/T、MSR급Tmin시진단간조종합정적령민지표,정량분석타액선동태현상대진단인다충면역성질병인기적간조종합정유교고적림상응용개치。
Objective:To evaluate the diagnostic value of quantitative analysis of dynamic salivary gland images In Sjogren’s syndrome(SSS). Methods:39 patients who have Sjogren’s syndrome and 18 normal volunteers have been pill injected99 m TcO4-through elbow vein then dynamic salivary gland scanned. they oral vitamin C administered 0. 1 g at the fifteenth minutes. Computer produced composite image including dynamic images,time-activity curves and functional index of all salivary glands were acquired automatically using the technique of region of interest( ROIs) and self-compiled software of the computer. Results:The Sjogren’ s syndrome group compared normal volunteers group,UR,S/T and MSR were obviously below, Tmin was obviously exceed. Difference is significance, P < 0. 001. Conclusion:UR,SIT,MSR and Tmin are sensitive index to diagnose Sjogren’ s syndrome,Quantitative analysis of dynamic salivary gland images would be value in clinical application to diagnosis Sjogren’ s syndrome it be induced by various immune disease.