CAJ | 학술논문

ACS的临床表现可为，胸闷、胸痛伴气短、出汗，心衰，心律失常以及猝死。并伴有冠脉血管痉挛，管腔明显狭窄，甚至完全被堵塞，从而出现心肌缺血缺氧，严重时心肌坏死[1]。近年来研究发现：其进展过程中伴随的生化标记物超敏C反应蛋白、D-二聚体的改变可帮助临床医师及早识别病人的临床症状并为心电图改变不典型病人提供积极个体化的治疗方案，同时对评估其病情及预后、起到极大的作用。现将对急性冠脉综合征中( ACS)超敏C反应蛋白联合D-二聚体检测的研究进展进行综述。
ACS적림상표현가위，흉민、흉통반기단、출한，심쇠，심률실상이급졸사。병반유관맥혈관경련，관강명현협착，심지완전피도새，종이출현심기결혈결양，엄중시심기배사[1]。근년래연구발현：기진전과정중반수적생화표기물초민C반응단백、D-이취체적개변가방조림상의사급조식별병인적림상증상병위심전도개변불전형병인제공적겁개체화적치료방안，동시대평고기병정급예후、기도겁대적작용。현장대급성관맥종합정중( ACS)초민C반응단백연합D-이취체검측적연구진전진행종술。
Acute coronary symdrome( ACS) is caused by cononary atherosclerosis rupture, platelet adhesion, platelet aggregation, platelet release, through which the coagulation system is activated leading to the blood clot. ACS is usually accompanied by vasospasm,stenosis of arte-rioles,even worse,myocardial ischemia from completely blocking and myocardial necrosis. The research tells us that through biochemical marker-hyper sensitive C reactive protein and D-dimer ( increase ) , phisician can recognize some symdromes in early time,help ACS patients with atypical ECG changes and give them individual treatment;in addition,the two marker also play an important role in evaluating severity and prognosis. This review will present development in application of hyper-sensitive C reative protein and D-dimer in ACS.