CAJ | 학술논문

目的：探讨酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效。方法选取2011—2013年沧州市中心医院急诊科收治的肾绞痛患者457例，随机分为治疗组（228例）与对照组（229例）。治疗组患者予以酮咯酸氨丁三醇联合山莨菪碱治疗，对照组患者予以盐酸哌替啶联合山莨菪碱治疗。观察两组患者临床疗效及不良反应（如恶心、呕吐、头晕、尿潴留、低血压、过敏等）发生情况。结果两组患者总有效率比较，差异无统计学意义（ P ＞0.05）；治疗组患者不良反应发生率低于对照组，差异有统计学意义（P ＜0.05）。结论酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效显著，且不良反应少，安全性高。
목적：탐토동각산안정삼순연합산랑탕감치료신교통적료효。방법선취2011—2013년창주시중심의원급진과수치적신교통환자457례，수궤분위치료조（228례）여대조조（229례）。치료조환자여이동각산안정삼순연합산랑탕감치료，대조조환자여이염산고체정연합산랑탕감치료。관찰량조환자림상료효급불량반응（여악심、구토、두훈、뇨저류、저혈압、과민등）발생정황。결과량조환자총유효솔비교，차이무통계학의의（ P ＞0.05）；치료조환자불량반응발생솔저우대조조，차이유통계학의의（P ＜0.05）。결론동각산안정삼순연합산랑탕감치료신교통적료효현저，차불량반응소，안전성고。
Objective To explore the effect of ketorolac tromethamine and anisodamin in treatment of renal colic. Methods A total of 457 patients with renal colic were selected in Cangzhou Central Hospital from 2011 to 2013,they were ran-domly divided into treatment group(228 cases)and control group(229 cases). Traetment group was treated with ketorolac tromethamine and anisodamine,control group was treated with pethidine hydrochloride and anisodamine. Clinical effect and ad-verse reactions( such as nausea,vomiting,dizziness,urinary retention,low blood pressure,allergies) between the two groups were compared. Results The total effective rate showed no significant differences between the two groups(P > 0. 05), the adverse reactions rate of treatment group was lower than that of control group( P < 0. 05). Conclusion Ketorolac tromethamine and anisodamine has notable curative effect in the treatment of renal colic,has less adverse reactions and high safety.