CAJ | 학술논문

目的：探讨头孢菌素类抗生素的不良反应及对策。方法选取2012年1月－2014年1月医院使用头孢菌素治疗致严重不良反应的132例患者的临床资料，对不良反应类型、诱发因素及防治措施进行统计分析。结果诱发患者不良反应的因素包括：患者个体因素、药物因素、疾病因素、气候和环境因素等；不良反应类型包括：严重过敏反应、消化系统不良反应、神经系统不良反应、泌尿系统和血液系统不良反应，需采取积极地预防措施。结论头孢菌素类不良反应类型及诱发因素多样，临床上应针对患者的体质和病情进行全面判断，控制用法用量，预防不良反应发生。
목적：탐토두포균소류항생소적불량반응급대책。방법선취2012년1월－2014년1월의원사용두포균소치료치엄중불량반응적132례환자적림상자료，대불량반응류형、유발인소급방치조시진행통계분석。결과유발환자불량반응적인소포괄：환자개체인소、약물인소、질병인소、기후화배경인소등；불량반응류형포괄：엄중과민반응、소화계통불량반응、신경계통불량반응、비뇨계통화혈액계통불량반응，수채취적겁지예방조시。결론두포균소류불량반응류형급유발인소다양，림상상응침대환자적체질화병정진행전면판단，공제용법용량，예방불량반응발생。
Objective To investigate the factors of cephalosporin adverse reactions and the countermeasures to reduce the incidence of adverse reactions.Methods Clinical data of 132 patients were selected from Jan 2012 to Jan 2014 in their hospital.The factors of cephalosporin adverse reactions were analyzed and prevention measures were adopted.Results The factors for cephalosporin adverse reactions included:patients individual factor,drug factor,disease factor,climate and environ-mental factor,et al.The adverse reaction types included:severe allergic reactions,digestive system reactions,nervous system re-actions,urinary system reactions and blood system reactions.It needed prevention measures.Conclusion The adverse reaction types and factors are variety.According to patients′constitution and condition,a comprehensive judgment should be done,and control the usage and dosage to reduce adverse reactions.