CAJ | 학술논문

目的探讨在治疗带状疱疹后期神经痛（PHN）时，普瑞巴林与加巴喷丁的临床效果。方法随机选取2012年8月至2014年2月于我院接受治疗的带状疱疹后期神经痛（PHN）患者80例，随机分2组，对照组采用加巴喷丁，观察组采用普瑞巴林，2组施予相同的护理方法，比较2组患者的疼痛视觉模拟评分（VAS评分）和治疗效果。结果2组患者病情均有明显好转（P＜0．05），但2组之间没有明显差异（P＞0．05），观察组的镇痛时间稍快于对照组，不良反应发生率少于对照组，临床疗效优于对照组，数据具有明显差异（P＜0．05）。结论普瑞巴林在治疗PHN时，既能快速有效地达到镇痛效果，又能在一定程度上减少不良反应的发生，临床效果明显优于加巴喷丁。
목적탐토재치료대상포진후기신경통（PHN）시，보서파림여가파분정적림상효과。방법수궤선취2012년8월지2014년2월우아원접수치료적대상포진후기신경통（PHN）환자80례，수궤분2조，대조조채용가파분정，관찰조채용보서파림，2조시여상동적호리방법，비교2조환자적동통시각모의평분（VAS평분）화치료효과。결과2조환자병정균유명현호전（P＜0．05），단2조지간몰유명현차이（P＞0．05），관찰조적진통시간초쾌우대조조，불량반응발생솔소우대조조，림상료효우우대조조，수거구유명현차이（P＜0．05）。결론보서파림재치료PHN시，기능쾌속유효지체도진통효과，우능재일정정도상감소불량반응적발생，림상효과명현우우가파분정。
Objective To compare the effect of lyrica and gabapentin on herpes zoster neuralgia patients .Methods 80 patients with late herpes zoster neuralgia (PHN) treated from August 2012 to February 2014 in our hospital were randomly selected as the re‐search subjects ,and they were randomly divided into the control group(40 cases) and the observation group(40 cases) .The con‐trol group accepted gabapentin therapy ,while the observation group was treated by lyrica .The two groups were given the same nursing method .Visual analog pain score (VAS score) and the therapeutic effect of two groups were compared .Results Two groups patients were improved obviously ,but there was no significant difference between the two groups (P>0 .05) .Compared with the control group ,the analgesic effect of the observation group was slightly faster than that of the control group .Compared with the control group in the clinical curative effect ,the observation group showed the incidence of adverse reaction was less than that of the control group .The observation group was better .There was obvious difference (P<0 .05) .Conclusions Pregabalin in the treatment for herpes zoster neuralgia (PHN) not only can quickly and efficiently achieve pain effect ,but also can reduce the incidence of the adverse reactions .The clinical effect is obviously better than that of gabapentin .