CAJ | 학술논문

目的：探讨疏肝和胃法治疗肝胃不和型功能性消化不良患者的疗效及作用机制。方法：90例FD患者随机分为3组：舒胃方组、木香顺气丸组、莫沙比利组，平均每组30例，分别给予相应药物治疗4周。检测患者血清胃泌素、血清NO及胃排空。结果：经舒胃方组治疗后，FD患者胃排空、血清胃泌素改善，血清NO含量明显降低，优于木香顺气丸（P<0.05）。结论：舒胃方是治疗FD的有效方，其作用机制可能是影响FD患者的神经递质，促进胃肠动力。
목적：탐토소간화위법치료간위불화형공능성소화불량환자적료효급작용궤제。방법：90례FD환자수궤분위3조：서위방조、목향순기환조、막사비리조，평균매조30례，분별급여상응약물치료4주。검측환자혈청위비소、혈청NO급위배공。결과：경서위방조치료후，FD환자위배공、혈청위비소개선，혈청NO함량명현강저，우우목향순기환（P<0.05）。결론：서위방시치료FD적유효방，기작용궤제가능시영향FD환자적신경체질，촉진위장동력。
Objective: To observe the clinical efficacy and mechanism of shuganhewei Therapy on Functional Dyspesia patients. Method: 90 patients were randomly divided into 3 groups: Shuweifang groups, muxiangshunqi pill groups, Mosapride groups. To observe the change of serum GAS, NO and gastric emptdrogs. Result: After treatmented by Shuweifang, the patients was increased in GAS, gastric emptdrogs and delayed in NO, Compared with muxiangshunqi pill group, the curative effect was Statistically significant (P<0.05). Conclusion: Shuweifang is effective for the treatment of FD, its mechanism may be affect patients with neurotransmitters, promote gastrointestinal dynamics.