中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
8期
64-66
,共3页
黄景彬%林清%陈雁秋%陈洁
黃景彬%林清%陳雁鞦%陳潔
황경빈%림청%진안추%진길
香砂六君子汤%恶性肿瘤%化疗%厌食症
香砂六君子湯%噁性腫瘤%化療%厭食癥
향사륙군자탕%악성종류%화료%염식증
The Xiangsha Liujunzi decoction%Malignant tumor%Chemotherapy%Anorexia
目的:观察香砂六君子汤加味治疗恶性肿瘤化疗后厌食症的临床疗效。方法:将60例全身化疗后出现中重度厌食症的恶性肿瘤患者随机分为治疗组和对照组,每组30例。治疗组给予香砂六君子汤加味,1剂/d,对照组给予甲羟孕酮片500mg/次,1次/d,两组均连服2周。在治疗前后分别对两组患者进行进行厌食评分,并进行组间比较。结果:与治疗前比较,治疗后两组厌食评分均降低,差异均有统计学意义(治疗组Z值为-3.279,P=0.001;对照组Z值为-3.027,P=0.002)。治疗组与对照组比较,治疗前后厌食评分并无显著性差异(Z值为-0.117,P=0.907)。结论:香砂六君子汤加味能明显改善恶性肿瘤患者化疗后厌食症症状,其疗效与甲羟孕酮片相当。
目的:觀察香砂六君子湯加味治療噁性腫瘤化療後厭食癥的臨床療效。方法:將60例全身化療後齣現中重度厭食癥的噁性腫瘤患者隨機分為治療組和對照組,每組30例。治療組給予香砂六君子湯加味,1劑/d,對照組給予甲羥孕酮片500mg/次,1次/d,兩組均連服2週。在治療前後分彆對兩組患者進行進行厭食評分,併進行組間比較。結果:與治療前比較,治療後兩組厭食評分均降低,差異均有統計學意義(治療組Z值為-3.279,P=0.001;對照組Z值為-3.027,P=0.002)。治療組與對照組比較,治療前後厭食評分併無顯著性差異(Z值為-0.117,P=0.907)。結論:香砂六君子湯加味能明顯改善噁性腫瘤患者化療後厭食癥癥狀,其療效與甲羥孕酮片相噹。
목적:관찰향사륙군자탕가미치료악성종류화료후염식증적림상료효。방법:장60례전신화료후출현중중도염식증적악성종류환자수궤분위치료조화대조조,매조30례。치료조급여향사륙군자탕가미,1제/d,대조조급여갑간잉동편500mg/차,1차/d,량조균련복2주。재치료전후분별대량조환자진행진행염식평분,병진행조간비교。결과:여치료전비교,치료후량조염식평분균강저,차이균유통계학의의(치료조Z치위-3.279,P=0.001;대조조Z치위-3.027,P=0.002)。치료조여대조조비교,치료전후염식평분병무현저성차이(Z치위-0.117,P=0.907)。결론:향사륙군자탕가미능명현개선악성종류환자화료후염식증증상,기료효여갑간잉동편상당。
Objective: To observe the curative effect of additive Xiangshaliujunzi decoction on anorexia induced by chemotherapy in patients with malignant tumor. Methods: Sixty malignant tumor patients with moderate to severe chemotherapy-induced anorexia were randomized into the treatment group and the control group, 30 in each group. The patients in the treatment group received Xiangshaliujunzi decoction once daily for 2 weeks, while the patients in the control group received oral medroxyprogesterone 500mg once daily for 2 weeks. All patients were evaluated with the severity of chemotherapy-induced anorexia at the end of two week treatment. Results: The anorexia levels of both groups after treatment were lower than before treatment,showing statistical difference when compared with before treatment (Z=-3.279,-3.027, respectively, andP=0.001,P=0.002, respectively). The anorexia difference before and after treatment of the treatment group showed no statistical difference when compared with the control group (Z=-0.117, andP=0.907). Conclusion: Xiangshaliujunzi decoction can obviously improve anorexia induced by chemotherapy in patients with malignant tumor, and may has an equivalent effect to medroxyprogesterone.