按摩与康复医学
按摩與康複醫學
안마여강복의학
Chinese Manipulation & Rehabilitation Medicine
2015年
9期
89-91
,共3页
近红外光谱技术%制川乌%中药配方颗粒%干燥工艺
近紅外光譜技術%製川烏%中藥配方顆粒%榦燥工藝
근홍외광보기술%제천오%중약배방과립%간조공예
near infrared spectroscopy%Radix Aconiti Preparata%herbs%pellet formula%drying process
目的：采用近红外光谱（NIR）法考察制川乌配方颗粒干燥工艺。方法：将同批制川乌浓缩液采用真空干燥法和喷雾干燥法分别进行干燥，对制川乌浓缩液进行干燥方法比较，考察较好地保留有效成分的方法。结果：制川乌配方颗粒优选干燥工艺为：料液相对密度1.10（60℃）、进风温度165℃、出风温度70℃下进行喷雾干燥；经相关性分析，单酯型生物碱NIR预测值与HPLC参考值的相关系数r=0.901，P<0.001，水分NIR预测值与烘干法参考值的相关系数r=0.880，P<0.001，说明NIR预测值与HPLC参考值、烘干法参考值的相关性较好，可用于制川乌喷干粉的相关成分快速检测。结论：NIR定量模型不仅可应用于制川乌饮片中的生物碱及水分预测，也可以较好地快速预测制川乌喷干粉中相应成分的含量，为下一道工序的连续进行打下良好基础。
目的：採用近紅外光譜（NIR）法攷察製川烏配方顆粒榦燥工藝。方法：將同批製川烏濃縮液採用真空榦燥法和噴霧榦燥法分彆進行榦燥，對製川烏濃縮液進行榦燥方法比較，攷察較好地保留有效成分的方法。結果：製川烏配方顆粒優選榦燥工藝為：料液相對密度1.10（60℃）、進風溫度165℃、齣風溫度70℃下進行噴霧榦燥；經相關性分析，單酯型生物堿NIR預測值與HPLC參攷值的相關繫數r=0.901，P<0.001，水分NIR預測值與烘榦法參攷值的相關繫數r=0.880，P<0.001，說明NIR預測值與HPLC參攷值、烘榦法參攷值的相關性較好，可用于製川烏噴榦粉的相關成分快速檢測。結論：NIR定量模型不僅可應用于製川烏飲片中的生物堿及水分預測，也可以較好地快速預測製川烏噴榦粉中相應成分的含量，為下一道工序的連續進行打下良好基礎。
목적：채용근홍외광보（NIR）법고찰제천오배방과립간조공예。방법：장동비제천오농축액채용진공간조법화분무간조법분별진행간조，대제천오농축액진행간조방법비교，고찰교호지보류유효성분적방법。결과：제천오배방과립우선간조공예위：료액상대밀도1.10（60℃）、진풍온도165℃、출풍온도70℃하진행분무간조；경상관성분석，단지형생물감NIR예측치여HPLC삼고치적상관계수r=0.901，P<0.001，수분NIR예측치여홍간법삼고치적상관계수r=0.880，P<0.001，설명NIR예측치여HPLC삼고치、홍간법삼고치적상관성교호，가용우제천오분간분적상관성분쾌속검측。결론：NIR정량모형불부가응용우제천오음편중적생물감급수분예측，야가이교호지쾌속예측제천오분간분중상응성분적함량，위하일도공서적련속진행타하량호기출。
Objective:To investigate the drying process of Radix Aconiti Preparata pellet formula with near infrared spectroscopy. Methods:Drying the same batch of Radix Aconiti Preparata concentrate by vacuum drying and spray drying, compared the two methods and investigated the better method that effective components could be protected. Results:The best drying process of Radix Aconiti Preparata pellet formula is:spray drying in situation of materials' relative density 1.10 (60℃), air-in temperature 165℃, air-out temperature 70℃;through correlation analysis, the correlation coefficent between NIR predictive value of monoester alkaloid and reference value of drying method r=0.901, P<0.001, the correlation coefficent be-tween NIR predictive value of water and reference value of drying method r=0.880, P<0.001, shows that the correlation between NIR predictive val-ue and reference value of HPLC, drying method, which can be used in the rapid detection of relevant components of Radix Aconiti Preparata spray dried powder. Conclusion:NIR quantitative model not only can be used to predict the alkaloid and water in Radix Aconiti Preparata pieces, but also can rapid predict the content of corresponding components in Radix Aconiti Preparata spray dried powder to lay the groundwork for the next continu-ous process.
