按摩与康复医学
按摩與康複醫學
안마여강복의학
Chinese Manipulation & Rehabilitation Medicine
2015年
10期
26-27
,共2页
脑卒中后抑郁%黛力新%阿米替林%老年%疗效%不良反应
腦卒中後抑鬱%黛力新%阿米替林%老年%療效%不良反應
뇌졸중후억욱%대력신%아미체림%노년%료효%불량반응
post-stroke depression%deanxit%amitriptyline%the elderly%efficacy%adverse reaction
目的：比较黛力新和阿米替林治疗老年脑卒中后抑郁的疗效。方法：58例患者随机分为黛力新组和阿米替林组，基于常规脑卒中治疗外分别口服黛力新及盐酸阿米替林，6周后比较两组汉密尔顿抑郁量表（HAMD）评分、综合疗效及不良反应。结果：治疗后两组患者HAMD评分均低于治疗前（P<0.05），且黛力新组显著低于阿米替林组（P<0.05）；黛力新组总有效率为86.2%，显著高于对照组的55.2%（P=0.02707<0.05）；黛力新组不良反应率显著低于阿米替林组（P<0.05）。结论：黛力新治疗老年脑卒中后抑郁的疗效优于阿米替林，且不良反应少，值得临床推广应用。
目的：比較黛力新和阿米替林治療老年腦卒中後抑鬱的療效。方法：58例患者隨機分為黛力新組和阿米替林組，基于常規腦卒中治療外分彆口服黛力新及鹽痠阿米替林，6週後比較兩組漢密爾頓抑鬱量錶（HAMD）評分、綜閤療效及不良反應。結果：治療後兩組患者HAMD評分均低于治療前（P<0.05），且黛力新組顯著低于阿米替林組（P<0.05）；黛力新組總有效率為86.2%，顯著高于對照組的55.2%（P=0.02707<0.05）；黛力新組不良反應率顯著低于阿米替林組（P<0.05）。結論：黛力新治療老年腦卒中後抑鬱的療效優于阿米替林，且不良反應少，值得臨床推廣應用。
목적：비교대력신화아미체림치료노년뇌졸중후억욱적료효。방법：58례환자수궤분위대력신조화아미체림조，기우상규뇌졸중치료외분별구복대력신급염산아미체림，6주후비교량조한밀이돈억욱량표（HAMD）평분、종합료효급불량반응。결과：치료후량조환자HAMD평분균저우치료전（P<0.05），차대력신조현저저우아미체림조（P<0.05）；대력신조총유효솔위86.2%，현저고우대조조적55.2%（P=0.02707<0.05）；대력신조불량반응솔현저저우아미체림조（P<0.05）。결론：대력신치료노년뇌졸중후억욱적료효우우아미체림，차불량반응소，치득림상추엄응용。
Objective:To compare the efficacy between deanxit and amitriptyline treating elderly post-stroke depression. Methods:58 patients were randomly divided into deanxit group and amitriptyline group, based on the conventional stroke treatment respectively with oral deanxit and amitripty-line hydrochloride, to compare the Hamilton Depression Scale (HAMD) score, comprehensive effect and side effect after 6 weeks of two groups. Re-sults:The HAMD scores of two groups after treatment were both lower than those before treatment (P<0.05), and deanxit group markedly lower than amitriptyline group (P<0.05); the total effective rate of deanxit group was 86.2%, significantly higher than that of control group by 55.2% (P=0.02707<0.05);adverse reaction rate of deanxit group was lower than that of amitriptyline group (P<0.05). Conclusion:Curative effect of deanxit treating elderly post-stroke depression is better than that of amitriptyline, with less adverse reactions, being worthy of clinical application.
