CAJ | 학술논문

目的：探讨肿瘤标志物CYFRA21-1测定对原发性肝癌的诊断价值。方法对原发性肝癌（PHC）组96例、肝良性疾病组52例（肝硬化组28例、乙肝、丙肝组24例）和正常对照组30例，检测血清CYFRA21-1水平并进行统计学分析。结果 PHC组血清CYFRA21-1水平明显高于肝良性疾病组和正常对照组，差异有统计学意义（P＜0.01），肝良性疾病组和正常对照组血清CYFRA21-1水平比较差异也有统计学意义（P＜0.01），但阳性检出率比较无统计学意义（P＞0.05）。PHC 组和肝良性疾病组血清CYFRA21-1阳性率分别为66.7%（64/96）、7.7%（4/52）。结论检测血清CYFRA21-1水平对原发性肝癌的监测和诊断有较高的价值。
목적：탐토종류표지물CYFRA21-1측정대원발성간암적진단개치。방법대원발성간암（PHC）조96례、간량성질병조52례（간경화조28례、을간、병간조24례）화정상대조조30례，검측혈청CYFRA21-1수평병진행통계학분석。결과 PHC조혈청CYFRA21-1수평명현고우간량성질병조화정상대조조，차이유통계학의의（P＜0.01），간량성질병조화정상대조조혈청CYFRA21-1수평비교차이야유통계학의의（P＜0.01），단양성검출솔비교무통계학의의（P＞0.05）。PHC 조화간량성질병조혈청CYFRA21-1양성솔분별위66.7%（64/96）、7.7%（4/52）。결론검측혈청CYFRA21-1수평대원발성간암적감측화진단유교고적개치。
Objective To study the value of tumor marker CYFRA21-1 detection in diagnosis of primary hepatic carcinoma.Methods Choosing three different groups, primary hepatic carcinoma group(96 cases), benign hepatic disease(52 cases) including 28 cases of hepatic cirrhosis and 24 cases of hepatitis b or c, control group(30 cases). Detecting serum level of CYFRA21-1 in the three groups, analyzing data by statistical methods. Results The serum level of CYFRA21-1 in primary hepatic carcinoma group is significantly higher than in benign hepatic disease group or control group(P<0.01). The serum level of CYFRA21-1 between the latter two groups have statistical sense (P<0.01), but the positive rates of CYFRA21-1 detection have no statistical sense(P>0.05). The positive rates of CYFRA21-1 detection in primary hepatic carcinoma group and benign hepatic disease are 66.7%(64/96) and 7.7%(4/52). ConclusionDetection serum level of CYFRA21-1 has high value in detecting and diagnosing primary hepatic carcinoma.