CAJ | 학술논문

目的：通过对慢性乙型肝炎患者血清铁蛋白的检测，探讨血清铁蛋白含量与肝脏受损之间的关系。方法选取2014年4月至9月在浙江大学医学院附属第一医院感染科住院的慢乙肝患者48例。另外选取40例肝功能正常的健康体检者作为健康对照组，收集基本资料同时检测两组血清铁蛋白水平进行比较分析。结果慢乙肝患者血清铁蛋白水平明显高于健康对照组(P<0.01)，且与丙氨酸氨基转移酶呈正相关性(r=0.528, P<0.001)。结论血清铁蛋白可作为肝脏受损的重要参考指标，对于判断病情、了解预后有着重要意义。
목적：통과대만성을형간염환자혈청철단백적검측，탐토혈청철단백함량여간장수손지간적관계。방법선취2014년4월지9월재절강대학의학원부속제일의원감염과주원적만을간환자48례。령외선취40례간공능정상적건강체검자작위건강대조조，수집기본자료동시검측량조혈청철단백수평진행비교분석。결과만을간환자혈청철단백수평명현고우건강대조조(P<0.01)，차여병안산안기전이매정정상관성(r=0.528, P<0.001)。결론혈청철단백가작위간장수손적중요삼고지표，대우판단병정、료해예후유착중요의의。
Objective To explore the relationship between the level of serum ferritin (SF) and liver damage by mesuring SF in patients with chronic hepatitis B (CHB). Methods Forty-eight CHB patients who hospitalized in the infections department of the first affiliated hospital of Zhejiang university's Medical college from April to September in 2014 were enrolled in our study. In ad-dition, 40 healthy check-up person with normal liver function were selected as healthy controls (HCs). At the same time, the basic data were collected and compared. Results The SF level of CHB patients significantly higher than HCs(P<0.01). There was signif-icant positive correlation between SF and alanine transaminase (ALT) (r=0.528, P<0.001). Conclusion SF may be served as an important reference index for liver damage, and with important significance in judging the condition and prognosis of CHB patients.