CAJ | 학술논문

目的：观察葛九汤治疗围绝经期综合征临床疗效。方法：将120名患者随机分为治疗组（60例）和对照组（60例），在宣传教育前提下，治疗组采用葛九汤加谷维素片口服。对照组采用安慰剂、谷维素片口服，连续用药60 d后，观察比较治疗前后Kupperman 评分、临床疗效及FSH、LH、E2水平。结果：两组患者Kupperman评分治疗后与治疗前比较，差异有统计学意义（P＜0.01），且治疗组优于对照组（P＜0.05）。治疗组临床疗效总有效率75%，对照组为40%，差异有统计学意义（P＜0.01）。治疗组治疗后，E2上升，FSH、LH 下降，与治疗前相比有统计学意义（P＜0.05）；对照组E2、FSH、LH 与治疗前比较差异无统计学意义（P＞0.05）；两组治疗后组间比较差异有统计学意义（P＜0.05）。结论：葛九汤能有效治疗女性围绝经期综合征，明显改善临床症状，并在一定程度上改善血清性激素水平。
목적：관찰갈구탕치료위절경기종합정림상료효。방법：장120명환자수궤분위치료조（60례）화대조조（60례），재선전교육전제하，치료조채용갈구탕가곡유소편구복。대조조채용안위제、곡유소편구복，련속용약60 d후，관찰비교치료전후Kupperman 평분、림상료효급FSH、LH、E2수평。결과：량조환자Kupperman평분치료후여치료전비교，차이유통계학의의（P＜0.01），차치료조우우대조조（P＜0.05）。치료조림상료효총유효솔75%，대조조위40%，차이유통계학의의（P＜0.01）。치료조치료후，E2상승，FSH、LH 하강，여치료전상비유통계학의의（P＜0.05）；대조조E2、FSH、LH 여치료전비교차이무통계학의의（P＞0.05）；량조치료후조간비교차이유통계학의의（P＜0.05）。결론：갈구탕능유효치료녀성위절경기종합정，명현개선림상증상，병재일정정도상개선혈청성격소수평。
Objective: To observe the effect of Ge Jiu Decoction on perimenopausal syndrome. Methods: 120 patients were randomly divided into treatment group (60 cases) and control group (60 cases). Under the precondition of propaganda and education, the treatment group was used Ge Jiu Decoction with oryzanol tablets; while the control group was given placebo and oryzanol tablets, for 60 days continuously. And then we observed and compared Kupperman scores clinical efficacy and FSH, LH, E2 levels before and after the treatment. Results: Kupperman scores in both groups after treatment compared with before treatment, the difference was statistically significant (P<0.01), and the treatment group is better than that of the control group (P<0.05). Clinical total effectiveness of treatment group was 75% while that of the control group was 40%, with the statistically significant difference (P<0.01). The treatment group after treatment, E2 increased and FSH and LH declined compared with that before treatment, with statistical signigicance (P<0.05); for the control group, E2, FSH and LH had no statistically significant difference compared with that before treatment (P>0.05); Comparison between the two groups after treatment group difference was statistically significant (P<0.05). Conclusion: Ge Jiu Decoction can effectively treat women perimenopausal syndrome which significantly improve the clinical symptoms, and to a certain extent, improve the serum sex hormone levels.