CAJ | 학술논문

目的：为临床安全合理的使用头孢曲松钠与含钙产品提供依据。方法查阅在我国上市后已修订了六版的罗氏芬说明书，比较各版本说明书中提到头孢曲松钠与含钙产品的用法用量、不良反应、注意事项、禁忌部分的变更，了解头孢曲松钠与含钙产品的合理使用方法。结果从2009年第四版至最新版说明书中均明确标注了：“除新生儿，其他患者可进行罗氏芬和含钙输液的序贯给药，在两次输液之间必须用相容液体充分冲洗输液管。”结论同时静脉使用头孢曲松钠与含钙药物时可按说明书中方法正确序贯使用，但在特殊人群和情况下仍需谨慎。
목적：위림상안전합리적사용두포곡송납여함개산품제공의거。방법사열재아국상시후이수정료륙판적라씨분설명서，비교각판본설명서중제도두포곡송납여함개산품적용법용량、불량반응、주의사항、금기부분적변경，료해두포곡송납여함개산품적합리사용방법。결과종2009년제사판지최신판설명서중균명학표주료：“제신생인，기타환자가진행라씨분화함개수액적서관급약，재량차수액지간필수용상용액체충분충세수액관。”결론동시정맥사용두포곡송납여함개약물시가안설명서중방법정학서관사용，단재특수인군화정황하잉수근신。
Objective To provide the information about the clinical safety and rational use of ceftriaxone with calcium products. Methods In order to gain the method of rational use of cetriaxone with calcium products, there is a need to compare the changes of usage and dosage, adverse reactions, attentions and compatibilities about the use of cetriaxone with calcium products in six different editions of rocephin label in our country. Results From the fourth edition in 2009 to the latest one, it has been marked clearly that rocephin and calcium-containing solutions may be administered sequentially of one another if the infusion lines are thoroughly flushed between infusions with a compatible fluid but except the neonatal. Conclusion According to the label, using the ceftriaxone with calcium products intravenously in sequential is allowed while it still needs to use carefully in special patients and conditions.