CAJ | 학술논문

目的：探讨癫?患者术前行韦达试验（Wada test）检测的意义。方法：回顾性分析广东三九脑科医院2012年2月～2013年10月收治的40例癫?患者术前治疗韦达试验检测结果。结果：在临床上诊断的40例癫?患者中，左利手3例，右利手37例。韦达试验结果，37例患者可以正确判断出语言及记忆优势半球，3例患者无法判断出语言及记忆优势半球。左侧大脑半球为语言、记忆优势半球的患者30例；双侧均参与语言功能的患者1例，左侧为语言优势半球，双侧记忆无侧别优势的患者4例；左侧为语言优势半球，双侧均有记忆代偿能力1例；右侧为语言、记忆优势半球7例；右侧为语言优势半球，双侧语言独立的患者1例；双侧均有记忆代偿能力的患者4例；双侧语言独立，双侧大脑半球无记忆侧别优势1例。39例患者可以判断运动功能的侧别，1例患者因麻醉药物过敏试验被迫中途终止。上述临床检测的结果分析，韦达试验术前评估患者语言及记忆功能优势侧半球及肢体肌力有效率达90％以上，具有很高的临床意义。结论：韦达试验是癫?术前评估患者语言及记忆功能优势侧半球及肢体肌力的重要手段，以及预测癫?术后患者语言、记忆及肢体功能的残疾程度，评估癫?手术可能风险，有利于癫?患者选择正确的治疗方式。
목적：탐토전?환자술전행위체시험（Wada test）검측적의의。방법：회고성분석엄동삼구뇌과의원2012년2월～2013년10월수치적40례전?환자술전치료위체시험검측결과。결과：재림상상진단적40례전?환자중，좌리수3례，우리수37례。위체시험결과，37례환자가이정학판단출어언급기억우세반구，3례환자무법판단출어언급기억우세반구。좌측대뇌반구위어언、기억우세반구적환자30례；쌍측균삼여어언공능적환자1례，좌측위어언우세반구，쌍측기억무측별우세적환자4례；좌측위어언우세반구，쌍측균유기억대상능력1례；우측위어언、기억우세반구7례；우측위어언우세반구，쌍측어언독립적환자1례；쌍측균유기억대상능력적환자4례；쌍측어언독립，쌍측대뇌반구무기억측별우세1례。39례환자가이판단운동공능적측별，1례환자인마취약물과민시험피박중도종지。상술림상검측적결과분석，위체시험술전평고환자어언급기억공능우세측반구급지체기력유효솔체90％이상，구유흔고적림상의의。결론：위체시험시전?술전평고환자어언급기억공능우세측반구급지체기력적중요수단，이급예측전?술후환자어언、기억급지체공능적잔질정도，평고전?수술가능풍험，유리우전?환자선택정학적치료방식。
Objective:To explore the clinical value of Wada test before operation for patients with epilepsy .Methods:A retrospective analysis of Wada test was made among 40 patients with epilepsy in the former Guangdong 999 Brain Hospital from February 2012 to October 2013 .Results:Through Wada clin‐cal tests among 40 patients with epilepsy including 3 left‐haded cases and 37 right‐handed cases ,37 pa‐tients could correctly cognize the words and memory dominant hemisphere ,while 3 cases could not ideati‐fy them .Left cerebral hemisphere as language and memory dominant hemisphere was found in 30 cases;1 case had bilateral language function;4 cases had left hemisphere as language advantage ,but without side advantage in bilateral memory ;I case had languge dominant hemisphere on left side with bilateral compen‐satory ablity ;7 cases had languge and memory dominant hemispbere on right side;I case had language dominant hemisphoere on right side with independant language ability ;4 cases had language compensatorg ability on both sides;I case had independant language ability ,but without memory advantage on both sides .All the 39 patients could judge the side diffenence of motor function ,while one case terminated dur‐ing anesthesia drug test .Conclusion:Wada test is an important means to assess the language and memory functions of dominant side hemisphere and limb muscle strength of patiemts with epilepsy ,and predict the degrees of language ,memory and physical function disability .It contribatses to selecting proper treatment through the assessment of possible risks of epilepstic surgery .