CAJ | 학술논문

目的：探讨红曲制剂血脂康胶囊对高脂血症的疗效及血管保护作用。方法：以我院收治的42例高脂血症患者为研究对象，随机分为治疗组和对照组，每组21例，治疗组给予血脂康治疗，对照组给予洛伐他汀药物进行治疗，观察治疗组与对照组治疗前后各项指标变化情况。结果：通过治疗，两组患者的临床症状均有所改善，红曲制剂血脂康的降脂疗效与洛伐他汀没有明显差异，两组患者的LDL/HDL、LDL-C比值明显低于治疗前，组间比较无显著差异。对照组治疗前后HDL-C比值变化较明显，差异具有统计学意义（P＜0.05）。结论：红曲制剂血脂康的降脂效果与缓解临床疗效值得肯定，能有效保护患者血管内皮，值得推广。
목적：탐토홍곡제제혈지강효낭대고지혈증적료효급혈관보호작용。방법：이아원수치적42례고지혈증환자위연구대상，수궤분위치료조화대조조，매조21례，치료조급여혈지강치료，대조조급여락벌타정약물진행치료，관찰치료조여대조조치료전후각항지표변화정황。결과：통과치료，량조환자적림상증상균유소개선，홍곡제제혈지강적강지료효여락벌타정몰유명현차이，량조환자적LDL/HDL、LDL-C비치명현저우치료전，조간비교무현저차이。대조조치료전후HDL-C비치변화교명현，차이구유통계학의의（P＜0.05）。결론：홍곡제제혈지강적강지효과여완해림상료효치득긍정，능유효보호환자혈관내피，치득추엄。
Objective:To study the curative effect of Monascus preparation Xuezhikang capsules on hyperlipidemia and blood vessel protection.Methods:42 patients with hyperlipidemia as the research objects in our hospital were,randomly divided into a treatment group and a control group,21 cases in each group.Patients in the treatment group were treated with Xuezhikang,while patients in the control group were treated with lovastatin,the changes of indicators before and after treatment of the treatment group and the control group were observed.Results:Through the treatment,the clinical symptoms of the two groups were improved,the effects of Monascus preparation Xuezhikang capsules had no significant differences with lovastatin,two groups of patients with LDL/HDL and LDL - C ratio were lower than those before the treatment.Compared the two groups,there was no significant difference between groups.The changes of HDL - C ratio in the control group before and after treatment were obvious with statistically significant difference (P<0.05).Conclusion:Monascus preparation Xuezhikang capsules has positive effects which can effectively protect the patient's blood vessel endothelium, worthy of promotion and application in clinic.