CAJ | 학술논문

目的：探讨18 F-脱氧葡萄糖（FDG）SPECT／CT显像（18 F-FDG显像）在食管癌术前分期中的价值。方法对38例诊断明确，完善相关检查后拟行食管癌切除术的初诊食管癌患者行18 F-FDG显像。其中18例手术治疗患者原发灶及区域淋巴结转移的18 F-FDG显像结果与病理学检查相比较；所有患者的远处转移灶及20例非手术治疗患者的区域淋巴结转移根据组织病理学活检、多种影像学检查临床随访而定，随访时间均大于6个月。结果在38例患者中，18 F-FDG显像检出了全部的原发灶，检出淋巴结转移24例，真阳性22例，真阴性10例，假阳性2例，假阴性4例，敏感度、特异度和准确度分别为84．6％（22／26）、83．3％（10／12）和84．2％（32／38），检出肝转移1例，肺转移1例。结论18 F-FDG显像能够提高食管癌患者分期的准确度，具有较好的临床应用价值。
목적：탐토18 F-탈양포도당（FDG）SPECT／CT현상（18 F-FDG현상）재식관암술전분기중적개치。방법대38례진단명학，완선상관검사후의행식관암절제술적초진식관암환자행18 F-FDG현상。기중18례수술치료환자원발조급구역림파결전이적18 F-FDG현상결과여병이학검사상비교；소유환자적원처전이조급20례비수술치료환자적구역림파결전이근거조직병이학활검、다충영상학검사림상수방이정，수방시간균대우6개월。결과재38례환자중，18 F-FDG현상검출료전부적원발조，검출림파결전이24례，진양성22례，진음성10례，가양성2례，가음성4례，민감도、특이도화준학도분별위84．6％（22／26）、83．3％（10／12）화84．2％（32／38），검출간전이1례，폐전이1례。결론18 F-FDG현상능구제고식관암환자분기적준학도，구유교호적림상응용개치。
Objective To investigate the diagnostic accuracy of single photon emission computed tomography /computed tomography (SPECT/CT)for the staging of esophageal carcinoma. Methods SPECT/CT scan was performed for 38 esophageal carcinoma patients new-ly diagnosed within the week before operation and radio- and/or chemo-therapy. The diagnosis of esophageal carcinoma was established ac-cording to the histopathology examination. In 18 patients with operation,the findings of SPECT/CT of regional lymph node metastasis were compared with the histopathology examination. The distant metastasis of all patients and the regional lymph node metastasis of 20 patients without operation were diagnosed by the pathological examination,other imaging findings or/and clinical follow up for over 6 months. Results All primary lesions were detected by 18 F-FDG imaging. 18 F-FDG imaging results in 24 of 38 patients showed lymph node metastasis,and marked abnormally increasing uptake of FDG. Of the 24 cases,22 cases were true positive,10 cases true negative,2 cases false positive, and 4 cases false negative. The sensitivity,specificity and accuracy was 84. 6%(22/26),83. 3%(10/12)and 84. 2%(32/38),respective-ly. 18 F-FDG imaging showed hepatic metastasis in 1 case and solitary lung metastasis in 1 case. Conclusion Molecular coincidence detec-tion with 18 F-FDG SPECT/CT scan shows a high sensitivity,specificity and accuracy in detecting primary esophageal cancer and metastases, and it is recommended in staging and treatment options of esophageal carcinoma.