CAJ | 학술논문

目的：观察化瘀疏肝汤治疗慢性乙型病毒性肝炎（乙型肝炎）肝纤维化的临床疗效。方法：将79例慢性乙型肝炎肝纤维化患者随机分为两组。对照组给予保肝对症治疗，治疗组在对照组的基础上加用化瘀疏肝汤，疗程3个月，观察治疗前后中医证候积分、肝纤维化指标、肝功能及B超检查的变化。结果：两组治疗后各项指标与治疗前比较，差异均有统计学意义，且治疗组优于对照组（P＜0．05）；治疗组有效率87．50％，对照组有效率66．67％，两组比较，差异有统计学意义（P＜0．05）。结论：化瘀疏肝汤治疗慢性乙型肝炎肝纤维化疗效显著，具有较好的抗纤维化作用，可改善患者临床症状和体征。
목적：관찰화어소간탕치료만성을형병독성간염（을형간염）간섬유화적림상료효。방법：장79례만성을형간염간섬유화환자수궤분위량조。대조조급여보간대증치료，치료조재대조조적기출상가용화어소간탕，료정3개월，관찰치료전후중의증후적분、간섬유화지표、간공능급B초검사적변화。결과：량조치료후각항지표여치료전비교，차이균유통계학의의，차치료조우우대조조（P＜0．05）；치료조유효솔87．50％，대조조유효솔66．67％，량조비교，차이유통계학의의（P＜0．05）。결론：화어소간탕치료만성을형간염간섬유화료효현저，구유교호적항섬유화작용，가개선환자림상증상화체정。
Objective:To observe the curative effect of Huayu Shugan Tang in treating chronic hepatitis B fibrosis.Methods:79 cases of patients with chronic hepatitis B with hepatic fibrosis were randomly divided into two groups.The control group was given Baogan symp-tomatic treatment and the treatment group was given Huayu Shugan Tang based on the control group,treatment for 3 months.Observed the symptom scores,liver fibrosis,liver function,changes and B ultrasound examination of two groups before and after treatment.Re-sults:Compared the indicators of two groups after treatment with before treatment,the difference was statistically significant,and the treatment group was better than that of the control group(P<0.05);the effective rate was 87.50%in treatment group and 66.67%in control group,the difference was statistically significant(P<0.05 ).Conclusion:Huayu Shugan Tang has obvious therapeutic effect on liver fibrosis in chronic hepatitis B patients and can improve the clinical symptoms and signs of patients.