临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2015年
6期
1027-1029
,共3页
呼吸机%氨溴索%RDS%PS%疗效
呼吸機%氨溴索%RDS%PS%療效
호흡궤%안추색%RDS%PS%료효
ventilator%ambroxol%RDS%PS%efficacy
目的：分析常频呼吸机联合大剂量氨溴索治疗新生儿呼吸窘迫综合征( RDS)的疗效。方法选择我院2011年3月-2014年3月72例RDS患儿,采用隐匿数字随机法分为两组,均采用常频呼吸机并给予综合治疗,对照组36例患儿给予肺泡表面活性物质,观察组36例患儿给予大剂量氨溴索静脉滴注,比较两组疗效、血气指标、临床相关指标及肺炎发生情况。结果治疗后48 h两组 PH 、PaO2、PaO2/FiO2较治疗前明显升高,PaCO2较治疗前明显下降(P<0．05),两组治疗前后各指标比较(P>0．05)。两组平均吸氧时间、机械通气平均时间、平均住院时间比较差异无显著性,观察组总有效率为86．11%,对照组总有效率为83．33(P>0．05)。观察组平均住院费用明显低于对照组,并发肺炎患儿明显少于对照组(P<0．05)。结论常频呼吸机联合大剂量氨溴索治疗RDS疗效与PS联合呼吸机基本相同,但费用较低,可减轻患儿家庭负担,及降低肺炎的发生率。
目的：分析常頻呼吸機聯閤大劑量氨溴索治療新生兒呼吸窘迫綜閤徵( RDS)的療效。方法選擇我院2011年3月-2014年3月72例RDS患兒,採用隱匿數字隨機法分為兩組,均採用常頻呼吸機併給予綜閤治療,對照組36例患兒給予肺泡錶麵活性物質,觀察組36例患兒給予大劑量氨溴索靜脈滴註,比較兩組療效、血氣指標、臨床相關指標及肺炎髮生情況。結果治療後48 h兩組 PH 、PaO2、PaO2/FiO2較治療前明顯升高,PaCO2較治療前明顯下降(P<0．05),兩組治療前後各指標比較(P>0．05)。兩組平均吸氧時間、機械通氣平均時間、平均住院時間比較差異無顯著性,觀察組總有效率為86．11%,對照組總有效率為83．33(P>0．05)。觀察組平均住院費用明顯低于對照組,併髮肺炎患兒明顯少于對照組(P<0．05)。結論常頻呼吸機聯閤大劑量氨溴索治療RDS療效與PS聯閤呼吸機基本相同,但費用較低,可減輕患兒傢庭負擔,及降低肺炎的髮生率。
목적：분석상빈호흡궤연합대제량안추색치료신생인호흡군박종합정( RDS)적료효。방법선택아원2011년3월-2014년3월72례RDS환인,채용은닉수자수궤법분위량조,균채용상빈호흡궤병급여종합치료,대조조36례환인급여폐포표면활성물질,관찰조36례환인급여대제량안추색정맥적주,비교량조료효、혈기지표、림상상관지표급폐염발생정황。결과치료후48 h량조 PH 、PaO2、PaO2/FiO2교치료전명현승고,PaCO2교치료전명현하강(P<0．05),량조치료전후각지표비교(P>0．05)。량조평균흡양시간、궤계통기평균시간、평균주원시간비교차이무현저성,관찰조총유효솔위86．11%,대조조총유효솔위83．33(P>0．05)。관찰조평균주원비용명현저우대조조,병발폐염환인명현소우대조조(P<0．05)。결론상빈호흡궤연합대제량안추색치료RDS료효여PS연합호흡궤기본상동,단비용교저,가감경환인가정부담,급강저폐염적발생솔。
Objective To analyze of the curative effect of ventilator combined with large dose of ambroxol in the treatment of respiratory distress syndrome of newborn. Methods 72 infants with RDS were randomly divided into two groups. All infants were given constant frequency respirator and comprehensive treatment. 36 cases in the control group were given pulmonary surfactant, and 36 cases in the observation group were given large dose of ambroxol hydrochloride. The incidence of pneumonia, curative effect, and blood gas indexes were compared between the two groups. Results After the treatment, the levels of PH, PaO2 , and PaO2/FiO2 increased significantly, and the level of PaCO2 decreased significantly (P<0. 05). There was no significant difference in average oxygen time, mechanical ventilation time, and average duration of hospital between the two groups ( P>0. 05 ) . The total effective rate was 86. 11% in the observation group, and 83. 33% in the control group (P>0. 05). The average hospitalization expen-ses in the observation group was significantly lower than that in the control group. The incidence of pneumonia was significantly lower in the observation group than in the control group (P<0. 05). Conclusion The curative effect of normal frequency ventilation combined with large dose of ambroxol hydrochloride is similar with PS combined with ventilator in the treatment of RDS, but its cost is lower, and it can reduce the incidence of pneumonia.
