临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2015年
6期
1067-1069
,共3页
嗜酸性粒细胞计数%白细胞介素17%免疫球蛋白E%支气管哮喘
嗜痠性粒細胞計數%白細胞介素17%免疫毬蛋白E%支氣管哮喘
기산성립세포계수%백세포개소17%면역구단백E%지기관효천
eosinophil count%interleukin 17%immunoglobulin E%bronchial asthma
目的：探讨白细胞介素17(IL-17)、嗜酸性粒细胞(EOS)和免疫球蛋白E(IgE)在支气管哮喘( BA)患儿中的表达水平及其相关性。方法选择93例轻中度支气管哮喘患儿缓解期和发作期IL-17、EOS和IgE水平,同期选择80例健康体检儿童为对照组。结果患儿组血清EOS计数、血清IL-17和IgE水平均显著上升,远高于对照组(P<0．05),EOS计数随血清IL-17增高而增高,两者呈现正相关性(r=0．794,P=0．003),而IgE和EOS计数、血清IL-17水平并无相关关系；哮喘发作期IgE水平较缓解期高(P<0．05),发作期患儿IgE水平和IL-17呈现出正相关性(r=0．583,P=0．007)。结论儿童支气管哮喘血清EOS计数、血清IL-17和IgE水平表达增高,可为判断病情提供理论依据。
目的：探討白細胞介素17(IL-17)、嗜痠性粒細胞(EOS)和免疫毬蛋白E(IgE)在支氣管哮喘( BA)患兒中的錶達水平及其相關性。方法選擇93例輕中度支氣管哮喘患兒緩解期和髮作期IL-17、EOS和IgE水平,同期選擇80例健康體檢兒童為對照組。結果患兒組血清EOS計數、血清IL-17和IgE水平均顯著上升,遠高于對照組(P<0．05),EOS計數隨血清IL-17增高而增高,兩者呈現正相關性(r=0．794,P=0．003),而IgE和EOS計數、血清IL-17水平併無相關關繫；哮喘髮作期IgE水平較緩解期高(P<0．05),髮作期患兒IgE水平和IL-17呈現齣正相關性(r=0．583,P=0．007)。結論兒童支氣管哮喘血清EOS計數、血清IL-17和IgE水平錶達增高,可為判斷病情提供理論依據。
목적：탐토백세포개소17(IL-17)、기산성립세포(EOS)화면역구단백E(IgE)재지기관효천( BA)환인중적표체수평급기상관성。방법선택93례경중도지기관효천환인완해기화발작기IL-17、EOS화IgE수평,동기선택80례건강체검인동위대조조。결과환인조혈청EOS계수、혈청IL-17화IgE수평균현저상승,원고우대조조(P<0．05),EOS계수수혈청IL-17증고이증고,량자정현정상관성(r=0．794,P=0．003),이IgE화EOS계수、혈청IL-17수평병무상관관계；효천발작기IgE수평교완해기고(P<0．05),발작기환인IgE수평화IL-17정현출정상관성(r=0．583,P=0．007)。결론인동지기관효천혈청EOS계수、혈청IL-17화IgE수평표체증고,가위판단병정제공이론의거。
Objective To evaluate the expression level of IL-17, EOS and IgE in the children with bronchial asthma and their correlation. Methods 93 children with bronchial asthma from April 2012 to February 2013 were chosen as the experimental objects, and another 80 health children were taken as the control group. The levels of IL-17, EOS and IgE during remission period and acute phase were compared between the two groups. Results EOS count, serum IL-17 and IgE levels increased more significantly in the experiment group than in the control group ( P<0. 05). EOS count was positively correlated with IL-17 (r=0. 794,P=0. 003). The level of IgE was higher at acute phase than in remission (P<0. 05). IgE and IL-17 showed a positive correlation at acute phase (r=0. 583, P=0. 007). Conclusion The high expression of EOS count, serum IL-17 and IgE can be used to diagnose the situa-tion of children with bronchial asthma.
