CAJ | 학술논문

目的：建立能同时测定消炎镇痛膏中樟脑、薄荷脑、冰片、水杨酸甲酯和麝香草酚5种组分含量的气相色谱方法。方法：采用DM－WAX毛细管色谱（30 m ×0．25μm，0．25μm）；柱温130℃；氢火焰离子化检测器，气化室温度为200℃；检测器温度230℃。结果：樟脑、薄荷脑、冰片、水杨酸甲酯、麝香草酚的峰面积与浓度呈现很好的线性关系。采用萘为内标物，可以准确测定样品中的5种有效成分。樟脑、薄荷脑、冰片、水杨酸甲酯、麝香草酚的回收率分别为100．06％、99．82％、99．23％、99．87％、100．14％。阴性样品不干扰测定。结论：该方法专属性好，准确率高，耐用范围好，可以作为产品质控方法。
목적：건립능동시측정소염진통고중장뇌、박하뇌、빙편、수양산갑지화사향초분5충조분함량적기상색보방법。방법：채용DM－WAX모세관색보（30 m ×0．25μm，0．25μm）；주온130℃；경화염리자화검측기，기화실온도위200℃；검측기온도230℃。결과：장뇌、박하뇌、빙편、수양산갑지、사향초분적봉면적여농도정현흔호적선성관계。채용내위내표물，가이준학측정양품중적5충유효성분。장뇌、박하뇌、빙편、수양산갑지、사향초분적회수솔분별위100．06％、99．82％、99．23％、99．87％、100．14％。음성양품불간우측정。결론：해방법전속성호，준학솔고，내용범위호，가이작위산품질공방법。
Objective:To grope for a kind of method,it can simultaneously determine five components in gas chromatography.This com-ponents include camphor,menthol and borneol,salicylic acid methyl ester and thymol in Xiaoyan Zhentong Gao.Methods:Using the DM-WAX polar capillary vessel chromatographic column (30 m ×0.25 μm and 0.25 μm);Column temperature 130 ℃;Hydrogen flame ionization detector,the gasification chamber temperature is 200 ℃;detector temperature is 230 ℃.Results:The negative samples with not interference measurement,the peak area and concentration of camphor,menthol,borneol,methyl salicylate,thymol show a good linear relationship.Using the naphthalene is internal standard substance,which can accurately measure the five kinds of effective com-ponents in the samples.This method has good durability and accuracy.The recovery rates of camphor,menthol,borneol,methyl salicy-late,thymol respectively are:100.06%,99.82%,99.23%,99.87%,100.14%.Conclusion:The method is specific,and high accura-cy,good durable range,can be used as a method of product quality control.