CAJ | 학술논문

目的：了解小儿支原体肺炎患儿应用阿奇霉素联合热毒宁进行治疗的临床疗效及安全性．方法：随机抽取本院近年来收治的支原体肺炎患儿100例，根据治疗方案将其分为对照组与观察组，对照组患儿在常规治疗基础上联合阿奇霉素，观察组患儿在对照组治疗基础上联合热毒宁，每组均有患儿50例．对比两组患儿临床治疗效果和不良反应事件发生率．结果：观察组患儿临床治疗总有效率为96．0％，明显优于对照组患儿治疗总有效率82．0％，差异有统计学意义（P＜0．05）；观察组患儿不良反应发生率为4．0％，相对于对照组患儿不良反应率6．0％，差异无统计学意义（P ＞0．05）．结论：对小儿支原体肺炎患儿应用阿奇霉素联合热毒宁方案治疗不但能够取得令人满意的临床治疗效果，而且不会增加患儿不良反应事件发生率，具有安全高效的优点，值得临床普及推广．
목적：료해소인지원체폐염환인응용아기매소연합열독저진행치료적림상료효급안전성．방법：수궤추취본원근년래수치적지원체폐염환인100례，근거치료방안장기분위대조조여관찰조，대조조환인재상규치료기출상연합아기매소，관찰조환인재대조조치료기출상연합열독저，매조균유환인50례．대비량조환인림상치료효과화불량반응사건발생솔．결과：관찰조환인림상치료총유효솔위96．0％，명현우우대조조환인치료총유효솔82．0％，차이유통계학의의（P＜0．05）；관찰조환인불량반응발생솔위4．0％，상대우대조조환인불량반응솔6．0％，차이무통계학의의（P ＞0．05）．결론：대소인지원체폐염환인응용아기매소연합열독저방안치료불단능구취득령인만의적림상치료효과，이차불회증가환인불량반응사건발생솔，구유안전고효적우점，치득림상보급추엄．
AIM:To investigate the clinical efficacy and safety of azithromycin combined reduning in treating mycoplasma pneu-monia in children.METHODS:A total of 100 children with my-coplasma pneumonia who were admitted to the hospital in recent years were randomly selected.According to treatment regime,pa-tients were divided into control group and the observation group, with 50 cases in each.Patients in the control group were treated by azithromycin besides conventional treatment,while the obser-vation group were treated by reduning besides the treatment of the control group.Clinical efficacy and adverse reactions were com-pared.RESULTS:The total efficiency of observation group was 96%,which was significantly higher than 82% of the control group,and the difference was statistically significant (P<0.05);the incidence rate of the observation group and control group were 4% and 6%respectively,and there was no statistical significance (P>0.05).CONCLUSION:The clinical efficacy and safety of azithromycin combined reduning in treating mycoplasma pneumo-nia in children can harvest satisfactory clinical effect without in-creasing adverse reactions.It is safe and worthy of clinical popu-larization.