医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2015年
8期
983-985
,共3页
被动抬腿试验%感染性休克%容量反应性%每搏量
被動抬腿試驗%感染性休剋%容量反應性%每搏量
피동태퇴시험%감염성휴극%용량반응성%매박량
Passive leg raising trial%Septic shock%Volume responsiveness%Stroke volume
目的:评价被动抬腿试验(PLR)预测感染性休克患者的容量反应性。方法:采用前瞻性、观察性队列研究设计方法,选择34例感染性休克患者,先后进行 PLR 和容量负荷试验(VE),分别在 PLR 前(基线)、PLR 期间和 VE 后用超声心动图(TTE)测量记录每搏量(SV)并记录血流动力学变化。根据对容量负荷试验的反应(以 VE 后 SV 增加≥15%定义为有容量反应性)将患者分为有反应组和无反应组。用受试者工作特征曲线(ROC 曲线)评价 PLR 预测感染性休克患者的容量反应性。结果:34例患者中有反应组16例,无反应组18例。 VE 和 PLR 引起的ΔSV 存在显著直线相关性,Person 相关系数为0.630,P=0.000;PLR 诱导的ΔSV 预测感染性休克患者的容量反应性 ROC 曲线下面积(AUC)为0.866±0.064[95%可信区间(CI)为0.741~0.992,P=0.000],在 PLR 期间ΔSV 为11.84%时诊断容量反应性的敏感度为93.8%,特异度为72.2%。结论:PLR 在预测感染性休克患者的容量反应性具有良好的价值。
目的:評價被動抬腿試驗(PLR)預測感染性休剋患者的容量反應性。方法:採用前瞻性、觀察性隊列研究設計方法,選擇34例感染性休剋患者,先後進行 PLR 和容量負荷試驗(VE),分彆在 PLR 前(基線)、PLR 期間和 VE 後用超聲心動圖(TTE)測量記錄每搏量(SV)併記錄血流動力學變化。根據對容量負荷試驗的反應(以 VE 後 SV 增加≥15%定義為有容量反應性)將患者分為有反應組和無反應組。用受試者工作特徵麯線(ROC 麯線)評價 PLR 預測感染性休剋患者的容量反應性。結果:34例患者中有反應組16例,無反應組18例。 VE 和 PLR 引起的ΔSV 存在顯著直線相關性,Person 相關繫數為0.630,P=0.000;PLR 誘導的ΔSV 預測感染性休剋患者的容量反應性 ROC 麯線下麵積(AUC)為0.866±0.064[95%可信區間(CI)為0.741~0.992,P=0.000],在 PLR 期間ΔSV 為11.84%時診斷容量反應性的敏感度為93.8%,特異度為72.2%。結論:PLR 在預測感染性休剋患者的容量反應性具有良好的價值。
목적:평개피동태퇴시험(PLR)예측감염성휴극환자적용량반응성。방법:채용전첨성、관찰성대렬연구설계방법,선택34례감염성휴극환자,선후진행 PLR 화용량부하시험(VE),분별재 PLR 전(기선)、PLR 기간화 VE 후용초성심동도(TTE)측량기록매박량(SV)병기록혈류동역학변화。근거대용량부하시험적반응(이 VE 후 SV 증가≥15%정의위유용량반응성)장환자분위유반응조화무반응조。용수시자공작특정곡선(ROC 곡선)평개 PLR 예측감염성휴극환자적용량반응성。결과:34례환자중유반응조16례,무반응조18례。 VE 화 PLR 인기적ΔSV 존재현저직선상관성,Person 상관계수위0.630,P=0.000;PLR 유도적ΔSV 예측감염성휴극환자적용량반응성 ROC 곡선하면적(AUC)위0.866±0.064[95%가신구간(CI)위0.741~0.992,P=0.000],재 PLR 기간ΔSV 위11.84%시진단용량반응성적민감도위93.8%,특이도위72.2%。결론:PLR 재예측감염성휴극환자적용량반응성구유량호적개치。
Objective :To investigate the ability of passive leg raising (PLR) trial predicting volume responsiveness in septic shock .Methods :The prospective and observational cohort study was performed in 34 septic shock patients .PLR and volume expansion(VE) has been carried out successively .Respectively ,in front of the PLR (baseline) ,during the period of PLR and after VE using echocardiography measure stroke volume (SV) and hemodynamic changes in the re‐cord .According to the responsiveness of volume expansion (Responders were defined by the appearance of an increase in SV ≥ 15% after VE) ,patients were divided into responders and non‐responders .Using the receiver operating char‐acteristic curve (ROC curve) analysis PLR assessment of volume responsiveness in patients with septic shock .Results :A total of 34 patients were evaluated and resulting in 16 responders and 18 non‐responders .There was a positive corre‐lation between ΔSV caused by VE and PLR ,Person correlation coefficient of 0 .630 ,P = 0 .000 ;area under the ROC curve (AUC) of PLR‐induced ΔSV predicting volume responsiveness in septic shock were 0 .866 ± 0 .064(95% CI 0.741~ 0 .992 ,P= 0 .000) .The ΔSV ≥ 11 .84% during PLR was found to predict volume responsiveness with a sensitivity of 93 .8% ,specificity of 72 .2% .Conclusion :Passive leg raising (PLR) has good predictive value in the evaluation of vol‐ume responsiveness in patients with septic shock .