白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2015年
3期
190-192
,共3页
组织蛋白酶G%急性髓系白血病%免疫治疗
組織蛋白酶G%急性髓繫白血病%免疫治療
조직단백매G%급성수계백혈병%면역치료
Cathepsin G%Acute myeloid leukemia%Immunotherapy
组织蛋白酶G (CG)在中性粒细胞早幼粒阶段特异性升高,在多种急性髓系白血病(AML)中表达异常,是极具免疫活性的白血病相关抗原之一,为AML免疫治疗提供重要靶点,文章就CG在AML诊断及免疫治疗中的作用进行综述.
組織蛋白酶G (CG)在中性粒細胞早幼粒階段特異性升高,在多種急性髓繫白血病(AML)中錶達異常,是極具免疫活性的白血病相關抗原之一,為AML免疫治療提供重要靶點,文章就CG在AML診斷及免疫治療中的作用進行綜述.
조직단백매G (CG)재중성립세포조유립계단특이성승고,재다충급성수계백혈병(AML)중표체이상,시겁구면역활성적백혈병상관항원지일,위AML면역치료제공중요파점,문장취CG재AML진단급면역치료중적작용진행종술.
Cathepsin G (CG) is one of the serine proteases of neutrophils,and its mRNA is specifically increased in the promyelomonocytic stage of neutrophils and abnormal in several acute myeloid leukemias (AML).Meanwhile,CG is one of AML-associated antigens with strong immunocompetence,it is an important target of immunotherapy in AML.In this paper,the role of CG in the diagnosis and immunotherapy of AML were reviewed.
