CAJ | 학술논문

近十几年来对白血病基因突变的研究取得了很多进展,为认识各种白血病的生物学本质和发展规律带来了革新性的改变.基因突变的研究还改变着白血病的诊断、分类、预后、靶向治疗药物的研发和治疗方案的改进,显著改善了多种白血病的临床治疗效果.在2014年的第56届美国血液学会(ASH)年会上,相关主题学术报告依然占据了很大比重.文章结合近年来的相关研究进展、该次会议的报告内容以及笔者所在医院的工作经验作以介绍.
근십궤년래대백혈병기인돌변적연구취득료흔다진전,위인식각충백혈병적생물학본질화발전규률대래료혁신성적개변.기인돌변적연구환개변착백혈병적진단、분류、예후、파향치료약물적연발화치료방안적개진,현저개선료다충백혈병적림상치료효과.재2014년적제56계미국혈액학회(ASH)년회상,상관주제학술보고의연점거료흔대비중.문장결합근년래적상관연구진전、해차회의적보고내용이급필자소재의원적공작경험작이개소.
The study of gene mutations in leukemia has made great progress during the past decade,which brought innovative changes in understanding of the biological nature and development law of various leukemia.It improves not only the diagnosis,classification and prognosis of leukemia,but also the development of targeted drugs and therapy,which has greatly improved treatment of various types of leukemia.Research on gene mutations is still a hot topic in the 56th American Society of Hematology (ASH) annual meeting in 2014.Research progress in this area and related reports in the 56th ASH meeting will be introduced together with the authors' work experience in this article.