中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
7期
1518-1520
,共3页
张涓%梁耕田%黄文霞%刘莉%汪斌如%段冰玉
張涓%樑耕田%黃文霞%劉莉%汪斌如%段冰玉
장연%량경전%황문하%류리%왕빈여%단빙옥
颅脑损伤%医院感染%病原菌%耐药性
顱腦損傷%醫院感染%病原菌%耐藥性
로뇌손상%의원감염%병원균%내약성
Craniocerebral injury%Nosocomial infection%Pathogenic bacteria%Drug resistance
目的：探讨颅脑损伤患者术后医院感染病原菌特点、耐药性，为其为预防、治疗其感染提供参考依据。方法收集2009年3月－2013年3月201例颅脑损伤患者临床资料，记录患者医院感染发生率及发生部位，并分析病原菌种类和耐药性，采用SPSS17．0软件进行统计分析。结果201例患者中共有38例发生医院感染，感染率为18．91％；感染部位以呼吸系统为主，共13例占34．21％；共分离出59株病原菌，以革兰阴性菌为主，共36株占61．02％；其对常用抗菌药物均显示出较强的耐药性，其中对头孢哌酮、头孢唑林、庆大霉素的耐药率均＞60．0％。结论颅脑损伤患者术后医院感染病原菌主要是革兰阴性菌，根据药敏试验选择合适抗菌药物有助于预防、治疗术后感染的发生。
目的：探討顱腦損傷患者術後醫院感染病原菌特點、耐藥性，為其為預防、治療其感染提供參攷依據。方法收集2009年3月－2013年3月201例顱腦損傷患者臨床資料，記錄患者醫院感染髮生率及髮生部位，併分析病原菌種類和耐藥性，採用SPSS17．0軟件進行統計分析。結果201例患者中共有38例髮生醫院感染，感染率為18．91％；感染部位以呼吸繫統為主，共13例佔34．21％；共分離齣59株病原菌，以革蘭陰性菌為主，共36株佔61．02％；其對常用抗菌藥物均顯示齣較彊的耐藥性，其中對頭孢哌酮、頭孢唑林、慶大黴素的耐藥率均＞60．0％。結論顱腦損傷患者術後醫院感染病原菌主要是革蘭陰性菌，根據藥敏試驗選擇閤適抗菌藥物有助于預防、治療術後感染的髮生。
목적：탐토로뇌손상환자술후의원감염병원균특점、내약성，위기위예방、치료기감염제공삼고의거。방법수집2009년3월－2013년3월201례로뇌손상환자림상자료，기록환자의원감염발생솔급발생부위，병분석병원균충류화내약성，채용SPSS17．0연건진행통계분석。결과201례환자중공유38례발생의원감염，감염솔위18．91％；감염부위이호흡계통위주，공13례점34．21％；공분리출59주병원균，이혁란음성균위주，공36주점61．02％；기대상용항균약물균현시출교강적내약성，기중대두포고동、두포서림、경대매소적내약솔균＞60．0％。결론로뇌손상환자술후의원감염병원균주요시혁란음성균，근거약민시험선택합괄항균약물유조우예방、치료술후감염적발생。
OBJECTIVE To explore the pathogenic bacteria characteristics and prevention strategies of nosocomial infections in patients with craniocerebral injury after operation ,so as to provide reference for the prevention and treatment of the infections .METHODS The clinical data of 201 cases of craniocerebral injury patients in our hospi‐tal from Mar .2009 to Mar .2013 were collected .The incidence of nosocomial infections and infection sites were recorded .The types of pathogenic bacteria and their drug resistance were analyzed .All data were statistically ana‐lyzed by SPSS 17 .0 software .RESULTS Totally 38 cases in the all 201 patients appeared hospital infections and the infection rate was 18 .91% .Respiratory system was prone to be infected and 13 cases suffered from respiratory system infections ,accounting for 34 .21% .And a total of 59 strains of pathogenic bacteria were isolated ,inclu‐ding 36 strains of gram‐negative bacteria ,which accounted for 61 .20% .Gram‐negative bacteria were found to be highly resistant to common antibiotics ,especially cefoperazone ,cefazolin and gentamicin with the drug resistance rate of more than 60 .0% .CONCLUSION Gram‐negative bacteria were the main pathogenic bacteria which caused nosocomial infections in patients with craniocerebral injury .Antibiotics should be carefully chosen according to drug sensitive test so as to prevent and cure the postoperative infections .
