CAJ | 학술논문

目的：探讨神经外科患者耐甲氧西林金黄色葡萄球菌（M RS A ）感染部位分布及病原菌耐药性，以期为临床提供参考。方法回顾性分析医院2008年9月－2014年1月住院患者送检各类标本细菌培养及药敏试验结果，对确诊存在M RSA感染的61例患者细菌培养及药敏试验结果进行分析，采用SPSS16．0软件进行统计分析。结果神经外科61例M RS A感染患者感染部位主要为下呼吸道感染为主，共35例占57．38％；M RS A对青霉素、氨苄西林、头孢唑林、哌拉西林、头孢西丁、哌拉西林、克林霉素、阿奇霉素、左氧氟沙星耐药率达100．00％。结论神经外科M RS A感染患者感染部位以下呼吸道感染及切口感染多见，对临床多种抗菌药物完全耐药，了解M RS A的感染部位分布及耐药性，加强M RS A监测，合理使用抗菌药物，严格执行手卫生及消毒隔离等制度，避免M RS A的医院感染发生及传播。
목적：탐토신경외과환자내갑양서림금황색포도구균（M RS A ）감염부위분포급병원균내약성，이기위림상제공삼고。방법회고성분석의원2008년9월－2014년1월주원환자송검각류표본세균배양급약민시험결과，대학진존재M RSA감염적61례환자세균배양급약민시험결과진행분석，채용SPSS16．0연건진행통계분석。결과신경외과61례M RS A감염환자감염부위주요위하호흡도감염위주，공35례점57．38％；M RS A대청매소、안변서림、두포서림、고랍서림、두포서정、고랍서림、극림매소、아기매소、좌양불사성내약솔체100．00％。결론신경외과M RS A감염환자감염부위이하호흡도감염급절구감염다견，대림상다충항균약물완전내약，료해M RS A적감염부위분포급내약성，가강M RS A감측，합리사용항균약물，엄격집행수위생급소독격리등제도，피면M RS A적의원감염발생급전파。
OBJECTIVE To investigate distribution and resistance of pathogens in the neurosurgical methicillin‐resistant Staphylococcus aureus (MRSA) infections for clinical reference .METHODS The retrospective analysis was conducted on bacterial culture of all kinds of specimens and drug susceptibility test results for hospitalized pa‐tients in Sep .2008-Jan .2014 ,the bacterial culture and drug susceptibility test results were analyzed for the 61 confirmed cases of patients with MRSA infections (61 strains) .The software SPSS16 .0 was used for statistical a‐nalysis .RESULTS The 61 cases of neurosurgical MRSA infections were mainly lower respiratory tract infection (35 cases ,57 .38% ) .The resistant rate of MRSA was up to 100 .00% to penicillin ,ampicillin ,cefazolin ,pip‐eracillin ,cefoxitin ,piperacillin ,clindamycin ,azithromycin ,and levofloxacin .CONCLUSION Neurosurgical M R‐SA infection is mostly seen in lower respiratory tract and incision infections ,and completely resistant to many kinds of clinical antimicrobial agents .Clinicians should understand infection site distribution and drug resistance of MRSA infections ,strengthen surveillance of MRSA ,rationally use of antimicrobial agents ,and strict implement hand hygiene ,disinfection and isolation system so as to avoid nosocomial M RSA infections and transmission .