中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
7期
1536-1537,1540
,共3页
头孢哌酮/舒巴坦%脑卒中%肺部感染
頭孢哌酮/舒巴坦%腦卒中%肺部感染
두포고동/서파탄%뇌졸중%폐부감염
Cefoperazone/sulfate%Stroke%Pulmonary infection
目的：观察头孢他啶和头孢哌酮／舒巴坦治疗脑卒中合并肺部感染的临床效果，研究控制感染的依据和防范方法，为临床治疗提供参考依据。方法选取医院2010年3月－2013年10月脑卒中合并肺部感染334例符合标准的患者，随机分为对照组166例和观察组168例，对照组患者使用头孢他啶静脉滴注治疗，观察组患者使用头孢哌酮／舒巴坦静脉滴注治疗；治疗一个月后对比两组患者痰培养细菌清除率以及总有效率，采用SPSS18．0进行统计分析。结果治疗前，两组患者痰培养检出细菌334株，细菌清除率对照组为66．3％、观察组为88．1％；痊愈率对照组和观察组患者分别为32．1％和48．2％、总有效率分别为75．0％和95．2％，两组比较差异均有统计学意义。结论头孢哌酮／舒巴坦治疗脑卒中合并肺部感染的临床效果较好，安全性较高，值得信赖和临床上的广泛应用。
目的：觀察頭孢他啶和頭孢哌酮／舒巴坦治療腦卒中閤併肺部感染的臨床效果，研究控製感染的依據和防範方法，為臨床治療提供參攷依據。方法選取醫院2010年3月－2013年10月腦卒中閤併肺部感染334例符閤標準的患者，隨機分為對照組166例和觀察組168例，對照組患者使用頭孢他啶靜脈滴註治療，觀察組患者使用頭孢哌酮／舒巴坦靜脈滴註治療；治療一箇月後對比兩組患者痰培養細菌清除率以及總有效率，採用SPSS18．0進行統計分析。結果治療前，兩組患者痰培養檢齣細菌334株，細菌清除率對照組為66．3％、觀察組為88．1％；痊愈率對照組和觀察組患者分彆為32．1％和48．2％、總有效率分彆為75．0％和95．2％，兩組比較差異均有統計學意義。結論頭孢哌酮／舒巴坦治療腦卒中閤併肺部感染的臨床效果較好，安全性較高，值得信賴和臨床上的廣汎應用。
목적：관찰두포타정화두포고동／서파탄치료뇌졸중합병폐부감염적림상효과，연구공제감염적의거화방범방법，위림상치료제공삼고의거。방법선취의원2010년3월－2013년10월뇌졸중합병폐부감염334례부합표준적환자，수궤분위대조조166례화관찰조168례，대조조환자사용두포타정정맥적주치료，관찰조환자사용두포고동／서파탄정맥적주치료；치료일개월후대비량조환자담배양세균청제솔이급총유효솔，채용SPSS18．0진행통계분석。결과치료전，량조환자담배양검출세균334주，세균청제솔대조조위66．3％、관찰조위88．1％；전유솔대조조화관찰조환자분별위32．1％화48．2％、총유효솔분별위75．0％화95．2％，량조비교차이균유통계학의의。결론두포고동／서파탄치료뇌졸중합병폐부감염적림상효과교호，안전성교고，치득신뢰화림상상적엄범응용。
OBJECTIVE To observe the efficacy of ceftazidime and cefoperazone/sulfate in treatment of stroke accompanied by pulmonary infections and explore the basis for infection control and prevention methods ,so as to provide reference for clinical treatment .METHODS Totally 334 patients with stroke accompanied by pulmonary in‐fections from Mar .2010 to Oct .2013 who met inclusion criteria were enrolled and were randomly divided into the control group (n=166) and the observation group (n=168) .Patients in the control group were given intravenous infusion of ceftazidime ,while the observation group was given intravenous infusion of cefoperazone/sulfate .The two groups were compared for bacterial clearance rate by sputum culture and the total efficiency after one month of treatment .The software SPSS18 .0 was used for statistical analysis .RESULTS Before treatment ,the number of strains were 334 by sputum culture .The bacterial clearance rate was 66 .3% in the control group and 88 .1% in the observation group .The curative rate was 32 .1% and 48 .2% and the total efficiency was 75 .0% and 95 .2% in the control group and the observation group ,respectively .And there were significant differences between the two groups .CONCLUSION Cefoperazone/sulfate has good efficacy in treatment of stroke accompanied by pulmonary infections with high safety which is worthy of trust and clinically wide use .
