中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
7期
1547-1549
,共3页
抗菌药物%急性心肌梗死%医院感染%预防性使用
抗菌藥物%急性心肌梗死%醫院感染%預防性使用
항균약물%급성심기경사%의원감염%예방성사용
Antimicrobial drugs%Acute myocardial infarction%Hospital infection%Prophylactic use
目的：了解预防使用抗菌药物在心肌梗死（AMI）发生医院感染患者治疗中的作用，制定预防医院感染的策略，减少AM I患者的医院感染率。方法选取2012年1月－2013年6月AM I患者354例随机分为观察组183例和对照组171例，对照组按照A M I的常规治疗方法处理，观察组入院后预防性使用抗菌药物，观察两组患者住院时间、医院感染部位与发生率、病原菌分布，采用SPSS 20．0进行统计分析。结果两组AMI患者的住院时间、医院感染发生率比较，差异均无统计学意义；观察组检出6株肠杆菌科细菌中产ESBLs检出率为83．33％，对照组11株肠杆菌科细菌中产 ESBLs检出率为36．36％；观察组产 ESBLs菌检出率显著高于对照组（ P＜0．05）。结论预防性应用抗菌药物无法降低AMI患者医院感染率及缩短住院时间，却导致真菌与产ESBLs菌感染比例的升高、增加AMI治疗的难度。
目的：瞭解預防使用抗菌藥物在心肌梗死（AMI）髮生醫院感染患者治療中的作用，製定預防醫院感染的策略，減少AM I患者的醫院感染率。方法選取2012年1月－2013年6月AM I患者354例隨機分為觀察組183例和對照組171例，對照組按照A M I的常規治療方法處理，觀察組入院後預防性使用抗菌藥物，觀察兩組患者住院時間、醫院感染部位與髮生率、病原菌分佈，採用SPSS 20．0進行統計分析。結果兩組AMI患者的住院時間、醫院感染髮生率比較，差異均無統計學意義；觀察組檢齣6株腸桿菌科細菌中產ESBLs檢齣率為83．33％，對照組11株腸桿菌科細菌中產 ESBLs檢齣率為36．36％；觀察組產 ESBLs菌檢齣率顯著高于對照組（ P＜0．05）。結論預防性應用抗菌藥物無法降低AMI患者醫院感染率及縮短住院時間，卻導緻真菌與產ESBLs菌感染比例的升高、增加AMI治療的難度。
목적：료해예방사용항균약물재심기경사（AMI）발생의원감염환자치료중적작용，제정예방의원감염적책략，감소AM I환자적의원감염솔。방법선취2012년1월－2013년6월AM I환자354례수궤분위관찰조183례화대조조171례，대조조안조A M I적상규치료방법처리，관찰조입원후예방성사용항균약물，관찰량조환자주원시간、의원감염부위여발생솔、병원균분포，채용SPSS 20．0진행통계분석。결과량조AMI환자적주원시간、의원감염발생솔비교，차이균무통계학의의；관찰조검출6주장간균과세균중산ESBLs검출솔위83．33％，대조조11주장간균과세균중산 ESBLs검출솔위36．36％；관찰조산 ESBLs균검출솔현저고우대조조（ P＜0．05）。결론예방성응용항균약물무법강저AMI환자의원감염솔급축단주원시간，각도치진균여산ESBLs균감염비례적승고、증가AMI치료적난도。
OBJECTIVE To find out the role of preventive use of antimicrobial drugs in the treatment of patients with acute myocardial infarction (AMI) complicated with hospital infections ;so as to formulate prevention strate‐gy for hospital infections and to reduce hospital infection rates of patients with AMI .METHODS Totally 354 cases of AMI patients were selected in the hospital from Jan .2012 to Jun .2013 and they were randomly divided into 183 cases of the observation group and 171 of the control group .The control group was treated according to the con‐ventional method of treatment of AMI ,prophylactic use of antimicrobial agents in the observation group after ad‐mission .The length of hospital stay ,hospital infection sites ,incidence ,pathogen distribution of the two groups were observed .The results were analyzed by SPSS 20 .0 software .RESULTS There were no significant differences between average hospitalization time and incidence of nosocomial infection of the two groups of patients with AMI . A total of 6 strains of Enterobacteriaceae were found to produce ESBLs in the observation group and the detection rate was 83 .33% .And 11 strains of Enterobacteriaceae were found to produce ESBLs in the control group with the detection rate of 36 .36% .ESBLs production rate of the observation group was significantly higher than the control group (P<0 .05) .CONCLUSION Prophylactic antimicrobial agents can not reduce the rate of nosocomial infections and shorten the time of hospitalization of patients with AMI but lead to higher proportion of fungal in‐fections and ESBLs strains ,hence increase the difficulty of AMI treatment .
