CAJ | 학술논문

目的：探析医院假丝酵母菌属的分布及对氟康唑的敏感性，为防范重点科室患者假丝酵母菌属感染及提高治疗效果提供依据。方法选取医院2012年7月－2013年7月从真菌室分离到的假丝酵母菌属178株作为鉴定对象，采用科玛嘉假丝酵母菌属显色培养基鉴定菌种分布，以及微量稀释法检测对氟康唑的敏感性，采用SPSS 16．0进行统计分析。结果178株假丝酵母菌属中以白色假绿酵母菌为主，共140株占78．7％；白色假丝酵母菌对氟康唑的敏感率最高，敏感率为97．9％，其次为伏立康唑96．4％，伊曲康唑敏感率最低为82．1％，其他假绿酵母菌属也对氟康唑的敏感率最高。结论医院分离的假丝酵母菌属以白色假丝酵母菌为主，对氟康唑敏感。
목적：탐석의원가사효모균속적분포급대불강서적민감성，위방범중점과실환자가사효모균속감염급제고치료효과제공의거。방법선취의원2012년7월－2013년7월종진균실분리도적가사효모균속178주작위감정대상，채용과마가가사효모균속현색배양기감정균충분포，이급미량희석법검측대불강서적민감성，채용SPSS 16．0진행통계분석。결과178주가사효모균속중이백색가록효모균위주，공140주점78．7％；백색가사효모균대불강서적민감솔최고，민감솔위97．9％，기차위복립강서96．4％，이곡강서민감솔최저위82．1％，기타가록효모균속야대불강서적민감솔최고。결론의원분리적가사효모균속이백색가사효모균위주，대불강서민감。
OBJECTIVE To discuss and analyze the Candida distribution and drug sensitivity to fluconazole in the hospital so as to provide basis for preventing Candida infections in key departments in the hospital and improving clinical efficacy .METHODS Totally 178 strains of Candida were separated in fungi room from Jul .2012 to Jul . 2013 in the hospital .They were chosen as research objects .CHROMagar Candida chromogenic medium was ap‐plied to identify species distribution and microdilution method was applied to test sensibility to fluconazole .All da‐ta were analyzed by SPSS 16 .0 software .RESULTS Among 178 strains of Candida ,there were 78 .7% (140/178) Candida albicans .Drug sensibility rate of C .albicans to fluconazole was the highest of 97 .9% (137/140) ,sec‐ond by voriconazole with the rate of 96 .4% and least by itraconazole with the rate of 82 .1% .Other Candida was also the most sensitive to fluconazole .CONCLUSION Candida separated in our hospital are mainly C . albicans , and they are sensitive to fluconazole .