CAJ | 학술논문

目的：研究肺炎衣原体（CP）感染与慢性阻塞性肺疾病的相关性，为更好的指导临床治疗。方法从医院2011年9月－2013年9月收治的慢性阻塞性肺疾病患者中随机选择100例进行研究，按照实际情况分为急性加重期组（60例）和稳定期组（40例），并选择50名健康人员设为健康对照组；检测所有研究对象的C P抗体水平，采用SPSS 15．0进行分析。结果 CP‐IgM检出阳性率急性加重期组为61．7％，显著高于健康对照组的10．0％，（ P＜0．05）；C P‐Ig A 和Ig G检出阳性率健康对照组分别为20．0％和22．0％，均显著低于稳定期组的52．5％、57．5％和急性加重期组的53．3％、55．0％，差异均有统计学意义（ P＜0．05）。结论 C P感染和慢性阻塞性肺疾病之间具有一定的相关性。
목적：연구폐염의원체（CP）감염여만성조새성폐질병적상관성，위경호적지도림상치료。방법종의원2011년9월－2013년9월수치적만성조새성폐질병환자중수궤선택100례진행연구，안조실제정황분위급성가중기조（60례）화은정기조（40례），병선택50명건강인원설위건강대조조；검측소유연구대상적C P항체수평，채용SPSS 15．0진행분석。결과 CP‐IgM검출양성솔급성가중기조위61．7％，현저고우건강대조조적10．0％，（ P＜0．05）；C P‐Ig A 화Ig G검출양성솔건강대조조분별위20．0％화22．0％，균현저저우은정기조적52．5％、57．5％화급성가중기조적53．3％、55．0％，차이균유통계학의의（ P＜0．05）。결론 C P감염화만성조새성폐질병지간구유일정적상관성。
OBJECTIVE To explore the correlation between chronic Chlamydia pneumoniae (CP) infections and chronic obstructive pulmonary disease ,in order to better guide the clinical treatment .METHODS Totally 100 pa‐tients with chronic obstructive pulmonary disease in our hospital from Sep .2011 to Sep .2013 were selected ,and were divided into the acute exacerbation group (60 cases) and the stable stage group (40 cases) according to the actual situation .And 50 healthy subjects were selected as the healthy control group .The CP antibody level and St George′s Respiratory Questionnaire (SGRQ ) score forced vital capacity (FVC ) and forced expiratory volume in one second (FEV1) of all the patients were tested ,scored and compared .The software SPSS 15 .0 was used for a‐nalysis .RESULTS The detection rate of CP‐IgM in the acute exacerbation group was 61 .7% ,which was signifi‐cantly higher than that in the healthy control group (10 .0% ) (P<0 .05) .The detection rates of CP‐IgA and IgG in the healthy control group was 20 .0% and 22 .0% ,which were significantly lower than those in the stable stage group (52 .5% ,57 .5% ) and the acute exacerbation group (53 .3% ,55 .0% ) (all P< 0 .05) .CONCLUSION There is a certain correlation between chronic CP infections and chronic obstructive pulmonary disease .