中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
7期
1562-1564
,共3页
精神分裂%医院感染%肺部感染%病原学%治疗
精神分裂%醫院感染%肺部感染%病原學%治療
정신분렬%의원감염%폐부감염%병원학%치료
Schizophrenia%Nosocomial infections%Pulmonary infection%Etiology%T reatments
目的：探讨老年慢性精神分裂症患者肺部感染的常见病原菌分布及抗菌药物治疗敏感性，提高对老年慢性精神分裂症患者医院感染的认识，降低感染率。方法选取2009年3月－2013年12月老年慢性精神分裂症发生肺部感染的患者137例，取患者痰液标本进行病原菌培养和药物敏感试验，对结果进行统计，采用SPSS17．0软件进行统计分析。结果137例肺部感染患者共检出病原菌109株，检出率为79．56％；以革兰阴性菌为主，共76株占69．72％；革兰阴性菌对头孢哌酮／舒巴坦以及亚胺培南表现出了极高的药物敏感性，均达到93．42％，革兰阳性菌对替考拉宁以及万古霉素敏感，而对青霉素和磺胺甲噁唑／甲氧苄啶的敏感性较低，仅有6．25％和9．38％。结论导致老年慢性精神分裂症患者肺部感染的病原菌种类繁多、种类不同，对抗菌药物的敏感性也不同，在确诊之后可以首先给予经验性联合用药，对肺部感染进行控制；而在经验性用药之前，及时进行痰液培养及药敏试验，以便根据病原菌进行针对性的治疗，保证治疗效果。
目的：探討老年慢性精神分裂癥患者肺部感染的常見病原菌分佈及抗菌藥物治療敏感性，提高對老年慢性精神分裂癥患者醫院感染的認識，降低感染率。方法選取2009年3月－2013年12月老年慢性精神分裂癥髮生肺部感染的患者137例，取患者痰液標本進行病原菌培養和藥物敏感試驗，對結果進行統計，採用SPSS17．0軟件進行統計分析。結果137例肺部感染患者共檢齣病原菌109株，檢齣率為79．56％；以革蘭陰性菌為主，共76株佔69．72％；革蘭陰性菌對頭孢哌酮／舒巴坦以及亞胺培南錶現齣瞭極高的藥物敏感性，均達到93．42％，革蘭暘性菌對替攷拉寧以及萬古黴素敏感，而對青黴素和磺胺甲噁唑／甲氧芐啶的敏感性較低，僅有6．25％和9．38％。結論導緻老年慢性精神分裂癥患者肺部感染的病原菌種類繁多、種類不同，對抗菌藥物的敏感性也不同，在確診之後可以首先給予經驗性聯閤用藥，對肺部感染進行控製；而在經驗性用藥之前，及時進行痰液培養及藥敏試驗，以便根據病原菌進行針對性的治療，保證治療效果。
목적：탐토노년만성정신분렬증환자폐부감염적상견병원균분포급항균약물치료민감성，제고대노년만성정신분렬증환자의원감염적인식，강저감염솔。방법선취2009년3월－2013년12월노년만성정신분렬증발생폐부감염적환자137례，취환자담액표본진행병원균배양화약물민감시험，대결과진행통계，채용SPSS17．0연건진행통계분석。결과137례폐부감염환자공검출병원균109주，검출솔위79．56％；이혁란음성균위주，공76주점69．72％；혁란음성균대두포고동／서파탄이급아알배남표현출료겁고적약물민감성，균체도93．42％，혁란양성균대체고랍저이급만고매소민감，이대청매소화광알갑오서／갑양변정적민감성교저，부유6．25％화9．38％。결론도치노년만성정신분렬증환자폐부감염적병원균충류번다、충류불동，대항균약물적민감성야불동，재학진지후가이수선급여경험성연합용약，대폐부감염진행공제；이재경험성용약지전，급시진행담액배양급약민시험，이편근거병원균진행침대성적치료，보증치료효과。
OBJECTIVE To investigate the distribution of common pathogens infected by the lungs of elderly pa‐tients with chronic schizophrenia and sensitivity of antibiotics ,so as to improve the awareness of nosocomial infec‐tions in elderly patients with chronic schizophrenia and to decrease the infection rate .METHODS Totally 137 cases of pulmonary infected elderly patients with chronic schizophrenia from Mar .2009 to Dec .2013 were selected and their sputum samples were cultivated and drug sensitive test were conducted .The results were statistically ana‐lyzed by SPSS 17 .0 software .RESULTS Among the 137 cases ,109 strains of pathogenic bacteria were detected . The detection rate was 79 .56% .Gram‐positive bacteria dominated the majority and accounted for 76 strains (69 .72% ) .The gram‐negative bacteria were highly sensitive to cefoperazone/sulbactam and imipenem .The sensi‐tive rate reached 93 .42% .The gram‐positive bacteria were sensitive to teicoplanin and vancomycin while insensi‐tive to penicillin and sulfamethoxazole/trimethoprim with the sensitive rate of only 6 .25% and 9 .38% . CONCLUSION The pathogenic bacteria causing pulmonary infections in elderly patients with chronic schizophrenia are of a wide range and variety and they also own different sensitivity to various antibiotics .We can control the pulmonary infections by using combination therapy according to experience after the definite diagnosis .And before using the drugs ,we should cultivate sputum and test the drug sensitivity in time so as to treat the patients accord‐ing to characteristics of pathogens and guarantee the clinical effects .
