CAJ | 학술논문

目的：探讨无抽搐电休克治疗精神分裂症患者症状及改善执行功能的临床疗效。方法：选取医院收治的60例精神分裂症患者，随机均分为对照组（抗精神病药物常规治疗）和观察组（在抗精神病药物基础上给予无抽搐电休克治疗），通过PANSS评分和BRIEF-A执行功能量表评分对治疗前后患者的临床症状和执行功能进行评价。结果：观察组治疗后PANSS总分显著低于对照组（t=-2.623，P<0.05），一般精神病理因子分显著低于对照组（t=-2.333， P<0.05）。治疗后两组患者大部分执行功能项目都有显著改善。观察组各项指标分显著优于对照组（t=-6.632， P<0.05）。结论：无抽搐电休克治疗精神分裂症患者疗效确切，可显著改善临床症状总和执行功能。
목적：탐토무추휵전휴극치료정신분렬증환자증상급개선집행공능적림상료효。방법：선취의원수치적60례정신분렬증환자，수궤균분위대조조（항정신병약물상규치료）화관찰조（재항정신병약물기출상급여무추휵전휴극치료），통과PANSS평분화BRIEF-A집행공능량표평분대치료전후환자적림상증상화집행공능진행평개。결과：관찰조치료후PANSS총분현저저우대조조（t=-2.623，P<0.05），일반정신병리인자분현저저우대조조（t=-2.333， P<0.05）。치료후량조환자대부분집행공능항목도유현저개선。관찰조각항지표분현저우우대조조（t=-6.632， P<0.05）。결론：무추휵전휴극치료정신분렬증환자료효학절，가현저개선림상증상총화집행공능。
Objective:To explore the treatment outcome of modified electroconvulsive therapy (MECT) and the improvement of executive function to patients with schizophrenia. Methods:60 patients with schizophrenia were ran-domly divided into control group (conventional antipsychotic drug treatment) and observation group (antipsychotic drugs treatment and MECT), PANSS and BRIEF-A functional rating scale were used to evaluate patients' clinical symptoms and executive function before and after treatment. Results:The PANSS scores of observation group are sig-nificantly lower than control group (t=-2.623,P<0.05)after treatment. And the score of general mental pathological factor of observation group are significantly lower than control group (t=-2.333,P<0.05)after treatment. The most project of executive function have improved significantly after treatment in two groups, and total index score of observation group is significantly better than control group (t=-6.632,P<0.05). Conclusion:MECT proves definite efficacy to schizophrenia, which can improves the clinical symptoms and executive function significantly.