CAJ | 학술논문

目的：探讨发生慢性萎缩性胃炎患者危险因素，并对比不同方案治疗幽门螺杆菌阳性患者的临床效果，为临床诊治提供参考。方法选取2010年3月－2014年4月90例慢性萎缩性胃炎患者，列为萎缩组，选取同期94例慢性非萎缩性胃炎患者，列为非萎缩组，对比两组患者临床资料分析危险因素；将萎缩组50例 H p阳性患者随机分为观察组与对照组，每组各25例，进行不同治疗方案，对比分析两组患者治疗效果。结果年龄、胆汁反流、胃癌家族史、H p感染是慢性萎缩性胃炎危险因素；慢性萎缩性胃炎患者中观察组治疗有效率92．00％、对照组为80．00％，两组对比差异有统计学意义（ P＜0．05）。结论高龄、家族胃癌史、胆汁反流是慢性萎缩性胃炎危险因素，以叶酸为主的联合治疗方案治疗慢性萎缩性胃炎患者Hp阳性效果好。
목적：탐토발생만성위축성위염환자위험인소，병대비불동방안치료유문라간균양성환자적림상효과，위림상진치제공삼고。방법선취2010년3월－2014년4월90례만성위축성위염환자，렬위위축조，선취동기94례만성비위축성위염환자，렬위비위축조，대비량조환자림상자료분석위험인소；장위축조50례 H p양성환자수궤분위관찰조여대조조，매조각25례，진행불동치료방안，대비분석량조환자치료효과。결과년령、담즙반류、위암가족사、H p감염시만성위축성위염위험인소；만성위축성위염환자중관찰조치료유효솔92．00％、대조조위80．00％，량조대비차이유통계학의의（ P＜0．05）。결론고령、가족위암사、담즙반류시만성위축성위염위험인소，이협산위주적연합치료방안치료만성위축성위염환자Hp양성효과호。
OBJECTIVE To investigate risk factors for chronic atrophic gastritis and to compare the clinical effects of different treatments for Hp patients ,so as to provide a reference for clinical treatment .METHODS Totally 90 cases of patients with chronic atrophic gastritis were selected from Mar .2010 to Apr .2014 .They were set as a atrophy group .During the same period ,another 94 cases of patients with non‐chronic atrophic gastritis were se‐lected as non‐atrophy group .The risk factors were analyzed according to the comparison of the clinical data of the two groups .The patients in the atrophic group with 50 Hp cases were randomly divided into observation group and control group with 25 cases each .Different treatments were used in two groups and the clinical effect of the two groups were compared .RESULTS The age ,bile reflux ,family history of gastric cancer ,and Hp infections were risk factors for chronic atrophic gastritis .In observation group ,the therapy efficiency rate was 92 .00% and in the control group the treatment efficiency rate was 80 .00% .The difference was significant (P< 0 .05) . CONCLUSION Age ,family history of gastric cancer and bile reflux are risk factors for chronic atrophic gastritis , and folic acid‐based treatment has a good clinical effect for treating chronic atrophic gastritis .